Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 12/20 | 0.67 |
| ▸ | WNT3A | P56704 | 12/20 | 0.67 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15988717 | 0.87 | CTNNB1 (0.67) | CTNNB1WNT3AACHEHTR4SIGMAR1 | |
| SCHEMBL15988800 | 0.87 | CTNNB1 (0.65) | CTNNB1WNT3AACHEHTR4SIGMAR1 | |
| SCHEMBL15988720 | 0.87 | CTNNB1 (0.67) | CTNNB1WNT3AACHEHTR4SIGMAR1 | |
| SCHEMBL15988724 | 0.84 | CTNNB1 (0.69) | CTNNB1WNT3AACHEHTR4SIGMAR1 | |
| SCHEMBL15988705 | 0.84 | CTNNB1 (0.69) | CTNNB1WNT3AACHEHTR4SIGMAR1 | |
| SCHEMBL15980101 | 0.83 | CTNNB1 (0.74) | CTNNB1WNT3AACHEHTR4SIGMAR1 | |
| SCHEMBL15969098 | 0.80 | CTNNB1 (1.00) | CTNNB1WNT3AACHEHTR4SIGMAR1 | |
| SCHEMBL15979921 | 0.79 | CTNNB1 (0.71) | CTNNB1WNT3AACHEHTR4SIGMAR1 | |
| SCHEMBL15979917 | 0.78 | CTNNB1 (0.74) | CTNNB1WNT3AACHEHTR4SIGMAR1 | |
| SCHEMBL15969364 | 0.77 | CTNNB1 (1.00) | CTNNB1WNT3AACHEHTR4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014130869-A1 | GAMMA-DIKETONES AS WNT/BETA -CATENIN SIGNALING PATHWAY ACTIVATORS | SAMUMED, LLC (US) | 2014-08-28 | — | — | WO | disclosed |