Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 12/20 | 0.63 |
| ▸ | WNT3A | P56704 | 11/20 | 0.63 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15979848 | 0.90 | CTNNB1 (0.66) | CTNNB1WNT3AIDO1TDO2ALDH1A1 | |
| SCHEMBL15979902 | 0.83 | CTNNB1 (0.70) | CTNNB1WNT3AALDH1A1KMT2AHDAC8 | |
| SCHEMBL15979869 | 0.81 | CTNNB1 (0.71) | CTNNB1WNT3AIDO1TDO2NPC1 | |
| SCHEMBL15979860 | 0.80 | CTNNB1 (0.53) | CTNNB1WNT3AALDH1A1KMT2ANPC1 | |
| SCHEMBL15979748 | 0.80 | CTNNB1 (0.53) | CTNNB1WNT3AALDH1A1KMT2ANPC1 | |
| SCHEMBL15979877 | 0.79 | CTNNB1 (0.67) | CTNNB1WNT3AALDH1A1KMT2AHDAC8 | |
| SCHEMBL15979940 | 0.79 | CTNNB1 (0.72) | CTNNB1WNT3AIDO1TDO2ALDH1A1 | |
| SCHEMBL15979851 | 0.78 | CTNNB1 (0.66) | CTNNB1WNT3AIDO1TDO2ALDH1A1 | |
| SCHEMBL30441077 | 0.78 | CTNNB1 (1.00) | CTNNB1WNT3AHDAC8HDAC1NPC1 | |
| SCHEMBL15970013 | 0.78 | CTNNB1 (1.00) | CTNNB1WNT3AHDAC8HDAC1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014130869-A1 | GAMMA-DIKETONES AS WNT/BETA -CATENIN SIGNALING PATHWAY ACTIVATORS | SAMUMED, LLC (US) | 2014-08-28 | — | — | WO | disclosed |