SCHEMBL15988940

SCHEMBL15988940

c1ccc(-c2cccc3c2oc2c(-c4ccc(-n5c6ccccc6c6cc(-c7ccc8c(c7)c7ccccc7n8-c7ccccc7)ccc65)cc4)cccc23)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
ATM Q13315 1/20 0.47
PRKDC P78527 5/20 0.38
ALDH1A1 P00352 5/20 0.38
PIK3CD O00329 2/20 0.38
PIK3CA P42336 2/20 0.38
PIK3CB P42338 2/20 0.38
PIK3CG P48736 2/20 0.38
BRD4 O60885 2/20 0.38
BRD2 P25440 2/20 0.38
BRD3 Q15059 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
TSHR P16473 2/20 0.38
HSD17B10 Q99714 2/20 0.38
PDE2A O00408 1/20 0.38
PIK3C2A O00443 1/20 0.38
PIK3R2 O00459 1/20 0.38
PIK3C2B O00750 1/20 0.38
PDE5A O76074 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10165773 0.97 KDM4E (0.47) KDM4EL3MBTL1ATMPRKDCALDH1A1
SCHEMBL17885352 0.97 KDM4E (0.44) KDM4EL3MBTL1ATMPRKDCALDH1A1
SCHEMBL10165765 0.96 KDM4E (0.49) KDM4EL3MBTL1ATMPRKDCALDH1A1
SCHEMBL15988960 0.95 KDM4E (0.45) KDM4EL3MBTL1ATMPRKDCALDH1A1
SCHEMBL18020807 0.94 KDM4E (0.44) KDM4EL3MBTL1ATMPRKDCALDH1A1
SCHEMBL18020790 0.94 KDM4E (0.41) KDM4EL3MBTL1ATMPRKDCALDH1A1
SCHEMBL18020793 0.94 KDM4E (0.44) KDM4EL3MBTL1ATMPRKDCALDH1A1
SCHEMBL18020782 0.94 KDM4E (0.41) KDM4EL3MBTL1ATMPRKDCALDH1A1
SCHEMBL24677128 0.93 KDM4E (0.45) KDM4EL3MBTL1ATMPRKDCALDH1A1
SCHEMBL10038519 0.93 KDM4E (0.51) KDM4EL3MBTL1ATMPRKDCALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4186898-A1 COMPOSITION FOR ORGANIC ELECTRONIC COMPOUNDS Merck Patent GmbH (DE) 2023-05-31 EP disclosed
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
EP-3649213-B1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2021-06-23 EP disclosed
US-20200231578-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-07-23 US disclosed
US-20200216391-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-07-09 US disclosed
WO-2019233904-A1 ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2019-12-12 WO disclosed
WO-2019007867-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-01-10 WO disclosed
WO-2014129869-A1 ORGANIC FIELD EFFECT LIGHT-EMITTING DEVICE 주식회사 두산 (KR) 2014-08-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200216391-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO4C1, SLCO2A1 KDM4E 3376/4885L3MBTL1 3718/4885ATM 4360/4885
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO2A1, SLCO1B3 KDM4E 3745/4885L3MBTL1 3258/4885ATM 4632/4885
US-20200231578-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO2A1, SLCO1B3 KDM4E 3745/4885L3MBTL1 3258/4885ATM 4632/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.