Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.48 |
| ▸ | CNR1 | P21554 | 5/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15995212 | 0.88 | CNR2 (0.65) | CNR2CNR1CA12CA1CA2 | |
| SCHEMBL17388286 | 0.86 | CNR2 (0.65) | CNR2CNR1CA12CA1CA2 | |
| SCHEMBL15995288 | 0.80 | CNR2 (0.62) | CNR2CNR1 | |
| SCHEMBL15995461 | 0.79 | CNR2 (0.64) | CNR2CNR1 | |
| SCHEMBL15995078 | 0.75 | CNR2 (0.43) | CNR2CNR1PTGS2 | |
| SCHEMBL17388619 | 0.71 | CNR2 (0.49) | CNR2CNR1PTGS2 | |
| SCHEMBL17414505 | 0.71 | CNR2 (0.78) | CNR2CNR1 | |
| SCHEMBL17388374 | 0.70 | CNR2 (0.49) | CNR2CNR1PTGS2 | |
| SCHEMBL15995651 | 0.70 | CNR2 (0.49) | CNR2CNR1PTGS2 | |
| SCHEMBL16002345 | 0.70 | CNR2 (0.72) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580400-B2 | Cannabinergic nitrate esters and related analogs | NORTHEASTERN UNIVERSITY (US) | 2017-02-28 | — | — | US | claimed |
| US-20160002195-A1 | CANNABINERGIC NITRATE ESTERS AND RELATED ANALOGS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-07 | — | — | US | claimed |
| WO-2014134127-A1 | CANNABINERGIC NITRATE ESTERS AND RELATED ANALOGS | NORTHEASTERN UNIVERSITY (US) | 2014-09-04 | — | — | WO | claimed |
| US-10968206-B2 | Cannabinergic nitrate esters and related analogs | NORTHEASTERN UNIVERSITY (US) | 2021-04-06 | — | — | US | disclosed |
| US-20190225596-A1 | Cannabinergic Nitrate Esters And Related Analogs | NORTHEASTERN UNIVERSITY | 2019-07-25 | — | — | US | disclosed |
| US-10221164-B2 | Cannabinergic nitrate esters and related analogs | NORTHEASTERN UNIVERSITY (US) | 2019-03-05 | — | — | US | disclosed |
| US-20170210728-A1 | Cannabinergic Nitrate Esters And Related Analogs | NORTHEASTERN UNIVERSITY | 2017-07-27 | — | — | US | disclosed |
| US-9580400-B2 | Cannabinergic nitrate esters and related analogs | NORTHEASTERN UNIVERSITY (US) | 2017-02-28 | — | — | US | disclosed |
| US-20160002195-A1 | CANNABINERGIC NITRATE ESTERS AND RELATED ANALOGS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-07 | — | — | US | disclosed |
| WO-2014134127-A1 | CANNABINERGIC NITRATE ESTERS AND RELATED ANALOGS | NORTHEASTERN UNIVERSITY (US) | 2014-09-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160002195-A1 | CANNABINERGIC NITRATE ESTERS AND RELATED ANALOGS | CNR2, CNR1, CHRNB3 | CNR2 1/4885CNR1 2/4885CA12 2046/4885 |
| US-10968206-B2 | Cannabinergic nitrate esters and related analogs | CNR2, CNR1, CHRNB3 | CNR2 1/4885CNR1 2/4885CA12 2046/4885 |
| US-10221164-B2 | Cannabinergic nitrate esters and related analogs | CNR2, CNR1, CHRNB3 | CNR2 1/4885CNR1 2/4885CA12 2046/4885 |
| US-20190225596-A1 | Cannabinergic Nitrate Esters And Related Analogs | CNR2, CNR1, CHRNB3 | CNR2 1/4885CNR1 2/4885CA12 2046/4885 |
| US-20170210728-A1 | Cannabinergic Nitrate Esters And Related Analogs | CNR2, CNR1, CHRNB3 | CNR2 1/4885CNR1 2/4885CA12 2046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.