Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.41 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.41 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.41 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.41 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16000734 | 0.91 | CA12 (0.48) | TSHRSMN1; SMN2TDP1ALDH1A1HSD17B10 | |
| SCHEMBL12696253 | 0.90 | TSHR (0.46) | TSHRSMN1; SMN2TDP1ALDH1A1HSD17B10 | |
| SCHEMBL16000705 | 0.87 | TSHR (0.48) | TSHRSMN1; SMN2TDP1ALDH1A1HSD17B10 | |
| SCHEMBL31367286 | 0.86 | TSHR (0.47) | TSHRSMN1; SMN2TDP1ALDH1A1HSD17B10 | |
| SCHEMBL890883 | 0.86 | TSHR (0.47) | TSHRSMN1; SMN2TDP1ALDH1A1HSD17B10 | |
| SCHEMBL12696249 | 0.85 | TDP1 (0.45) | TSHRSMN1; SMN2TDP1ALDH1A1HSD17B10 | |
| SCHEMBL16000732 | 0.85 | ESR1 (0.47) | TSHRSMN1; SMN2TDP1ALDH1A1HSD17B10 | |
| SCHEMBL2638757 | 0.84 | TSHR (0.45) | TSHRSMN1; SMN2TDP1ALDH1A1HSD17B10 | |
| SCHEMBL9568749 | 0.84 | TSHR (0.48) | TSHRSMN1; SMN2TDP1ALDH1A1HSD17B10 | |
| SCHEMBL10966987 | 0.84 | TSHR (0.48) | TSHRSMN1; SMN2TDP1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9496502-B2 | Organic ionic compounds, compositions and electronic devices | MERCK PATENT GMBH (DE) | 2016-11-15 | — | — | US | disclosed |
| US-20140249606-A1 | ORGANIC IONIC COMPOUNDS, COMPOSITIONS AND ELECTRONIC DEVICES | MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) | 2014-09-04 | — | — | US | disclosed |