Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM2 | Q9P1W9 | 20/20 | 0.51 |
| ▸ | PIM3 | Q86V86 | 19/20 | 0.51 |
| ▸ | PIM1 | P11309 | 18/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11984874 | 0.91 | PIM2 (0.62) | PIM2PIM3PIM1 | |
| SCHEMBL11984593 | 0.91 | PIM2 (0.55) | PIM2PIM3PIM1 | |
| SCHEMBL15109511 | 0.83 | PIM2 (0.54) | PIM2PIM3PIM1 | |
| SCHEMBL11984476 | 0.83 | PIM2 (0.62) | PIM2PIM3PIM1 | |
| SCHEMBL11984647 | 0.79 | PIM2 (0.62) | PIM2PIM3PIM1 | |
| SCHEMBL11984743 | 0.79 | PIM2 (0.74) | PIM2PIM3PIM1 | |
| SCHEMBL11984296 | 0.78 | PIM2 (0.62) | PIM2PIM3PIM1 | |
| SCHEMBL11984456 | 0.77 | PIM2 (0.51) | PIM2PIM3PIM1 | |
| SCHEMBL11984742 | 0.77 | PIM2 (0.72) | PIM2PIM3PIM1 | |
| SCHEMBL11909095 | 0.76 | PIM2 (0.83) | PIM2PIM3PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140249135-A1 | PIM KINASE INHIBITORS AND METHODS OF THEIR USE | NOVARTIS AG (CH) | 2014-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140249135-A1 | PIM KINASE INHIBITORS AND METHODS OF THEIR USE | PIM1, PIM2, PIM3 | PIM2 2/4885PIM3 3/4885PIM1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.