SCHEMBL16004373

SCHEMBL16004373

COC(=O)CCn1c(=O)n(CCC#N)c(=O)n(CCC#N)c1=O

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.47
TSHR P16473 2/20 0.39
KAT2B Q92831 3/20 0.39
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36
PDE4C Q08493 1/20 0.36
PDE4D Q08499 1/20 0.36
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 2/20 0.35
P2RX3 P56373 5/20 0.35
MAPK1 P28482 2/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
NPC1 O15118 1/20 0.34
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16004374 1.00 NPSR1 (0.47) NPSR1TSHRKAT2BPDE4APDE4B
SCHEMBL11655337 0.86 TSHR (0.52) TSHRKAT2BKDM4EALDH1A1P2RX3
SCHEMBL10329440 0.79 APEX1 (0.53) TSHRKAT2BPDE4APDE4BPDE4C
SCHEMBL190388 0.78 NPSR1 (0.69) NPSR1TSHRPDE4APDE4BPDE4C
SCHEMBL7337761 0.75 SMN1; SMN2 (0.41) TSHRKAT2BKDM4EALDH1A1P2RX3
SCHEMBL24682696 0.74 APEX1 (0.61) TSHRKAT2BKDM4EALDH1A1P2RX3
SCHEMBL1050327 0.73
SCHEMBL17331142 0.72 NPSR1 (0.50) NPSR1PDE4APDE4BPDE4CPDE4D
SCHEMBL16004375 0.72 NPSR1 (0.58) NPSR1TSHRPDE4APDE4BPDE4C
SCHEMBL5360417 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11424482-B2 Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same MITSUBISHI CHEMICAL CORPORATION (JP) 2022-08-23 US disclosed
US-20190334208-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY USING SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2019-10-31 US disclosed
US-20150364794-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY USING SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2015-12-17 US disclosed
WO-2014133107-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY USING SAME 三菱化学株式会社 (JP) 2014-09-04 WO disclosed