Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL607475 | 1.00 | HTR2A (0.80) | HTR2ADRD3 | |
| SCHEMBL607399 | 0.93 | HTR2A (0.80) | HTR2ADRD3 | |
| SCHEMBL30855321 | 0.93 | HTR2A (0.80) | HTR2ADRD3 | |
| SCHEMBL4198893 | 0.90 | HTR2A (0.72) | HTR2ADRD3 | |
| SCHEMBL605287 | 0.90 | HTR2A (0.72) | HTR2ADRD3 | |
| SCHEMBL15859506 | 0.89 | HTR2A (1.00) | HTR2ADRD3 | |
| SCHEMBL4203864 | 0.89 | HTR2A (1.00) | HTR2ADRD3 | |
| SCHEMBL10164205 | 0.88 | HTR2A (0.62) | HTR2ADRD3 | |
| SCHEMBL1967397 | 0.87 | DRD3 (0.60) | HTR2ADRD3 | |
| SCHEMBL1967395 | 0.87 | DRD3 (0.60) | HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8829029-B2 | Dual modulators of 5HT2A and D3 receptors | HOFFMANN-LA ROCHE INC. (US) | 2014-09-09 | — | — | US | disclosed |