⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29394145 | 0.64 | — | — | |
| SCHEMBL4146881 | 0.64 | — | — | |
| SCHEMBL73936 | 0.62 | — | — | |
| SCHEMBL9220672 | 0.62 | — | — | |
| SCHEMBL7048242 | 0.61 | — | — | |
| SCHEMBL3999555 | 0.59 | — | — | |
| SCHEMBL19553620 | 0.58 | — | — | |
| SCHEMBL3602506 | 0.53 | — | — | |
| SCHEMBL361626 | 0.43 | — | — | |
| SCHEMBL12992748 | 0.31 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104473932-B | Treat the pharmaceutical composition of inflammation of the central nervous system demyelinating disease and its purposes of administering drug combinations | 温州医科大学附属第医院 | 2017-06-20 | — | — | CN | claimed |
| US-20240400573-A1 | METHOD FOR MAKING A SUBSTITUTED IMIDAZO PYRAZOLE | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2024-12-05 | — | — | US | disclosed |
| US-12139493-B2 | Process for preparing substituted imidazo[4,5-c]pyrazoles | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2024-11-12 | — | — | US | disclosed |
| US-12103932-B2 | Process for preparing substituted imidazo[4,5-c]pyrazoles | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2024-10-01 | — | — | US | disclosed |
| US-20240287083-A1 | SOLUTION REFLUX PROCESS FOR MAKING SUBSTITUTED IMIDAZO PYRAZOLES | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2024-08-29 | — | — | US | disclosed |
| US-12012467-B2 | Small molecule DCN1 inhibitors and therapeutic methods using the same | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-18 | — | — | US | disclosed |
| US-11987585-B2 | Process for preparing substituted imidazo[4,5-c]pyrazoles | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2024-05-21 | — | — | US | disclosed |
| US-11987585-B2 | Process for preparing substituted imidazo[4,5-c]pyrazoles | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2024-05-21 | — | — | US | disclosed |
| US-20240076298-A1 | SYNTHESIS METHOD FOR IMIDAZO PYRAZOLES | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2024-03-07 | — | — | US | disclosed |
| US-20230183254-A1 | METHOD OF MAKING SUBSTITUTED IMIDAZO[4,5-c]PYRAZOLES | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2023-06-15 | — | — | US | disclosed |
| US-20050107399-A1 | Cytokine inhibitors | KEMIA, INC. | 2005-05-19 | — | — | US | disclosed |
| US-20040224974-A1 | 7-phenylpyrazolopyridine compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-11-11 | — | — | US | disclosed |
| US-6174912-B1 | FOR TREATING PSYCHIATRIC DISORDERS AND NEUROLOGICAL DISEASES INCLUDING MAJOR DEPRESSION, ANXIETY-RELATED DISORDERS, POST-TRAUMATIC STRESS DISORDER, SUPRANUCLEAR PALSY AND FEEDING DISORDERS AS WELL AS TREATMENT OF IMMUNOLOGICAL DISEASES | DUPONT PHARMACEUTICALS COMPANY | 2001-01-16 | — | — | US | disclosed |
| US-6174912-B1 | FOR TREATING PSYCHIATRIC DISORDERS AND NEUROLOGICAL DISEASES INCLUDING MAJOR DEPRESSION, ANXIETY-RELATED DISORDERS, POST-TRAUMATIC STRESS DISORDER, SUPRANUCLEAR PALSY AND FEEDING DISORDERS AS WELL AS TREATMENT OF IMMUNOLOGICAL DISEASES | DUPONT PHARMACEUTICALS COMPANY | 2001-01-16 | — | — | US | disclosed |
| EP-0937081-A1 | NITROGEN SUBSTITUTED IMIDAZO 4,5-c]PYRAZOLES AS CORTICOTROPIN RELEASING HORMONE ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 1999-08-25 | — | — | EP | disclosed |
| WO-1999010350-A1 | NITROGEN SUBSTITUTED IMIDAZO[4,5-c]PYRAZOLES AS CORTICOTROPIN RELEASING HORMONE ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |
| US-5389660-A | Hypotensive agents | MERCK & CO., INC. (US) | 1995-02-14 | — | — | US | disclosed |
| US-5164407-A | Hypotensive agents | MERCK & CO., INC. (US) | 1992-11-17 | — | — | US | disclosed |
| EP-0407102-A1 | Substituted imidazo-fused 5-membered ring heterocycles as angiotensin II antagonists | MERCK & CO. INC. (US) | 1991-01-09 | — | — | EP | disclosed |
| EP-0190457-A1 | Derivatives of 3-methyl-imidazo [4,5-c]pyrazole having therapeutic activity and a process for the preparation theref | CAMILLO CORVI S.p.A. (IT) | 1986-08-13 | — | — | EP | disclosed |