Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1386336 | 0.95 | SCD (0.69) | SCDDCTPP1 | |
| SCHEMBL1383922 | 0.94 | SCD (0.77) | SCDDCTPP1 | |
| SCHEMBL1385282 | 0.89 | SCD (0.77) | SCDDCTPP1 | |
| SCHEMBL1599652 | 0.88 | SCD (0.80) | SCDDCTPP1 | |
| SCHEMBL937537 | 0.87 | SCD (0.89) | SCDDCTPP1 | |
| SCHEMBL1384433 | 0.86 | SCD (0.76) | SCDDCTPP1 | |
| SCHEMBL2468894 | 0.86 | SCD (0.57) | SCDDCTPP1 | |
| SCHEMBL1599640 | 0.83 | SCD (0.88) | SCDDCTPP1 | |
| SCHEMBL1385471 | 0.83 | SCD (0.78) | SCDDCTPP1 | |
| SCHEMBL1385398 | 0.82 | SCD (0.60) | SCDDCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651620-B1 | PIPERAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2011-11-09 | — | — | EP | claimed |
| EP-1846035-B1 | COMBINATION THERAPY | XENON PHARMACEUTICALS INC (CA) | 2011-09-21 | — | — | EP | claimed |
| EP-1651620-B1 | PIPERAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2011-11-09 | — | — | EP | disclosed |
| US-8030488-B2 | Piperazine derivatives as stearoyl-coa desaturase inhibitors and their use as therapeutic agents | XENON PHARMACEUTICALS INC. (CA) | 2011-10-04 | — | — | US | disclosed |
| EP-1846035-B1 | COMBINATION THERAPY | XENON PHARMACEUTICALS INC (CA) | 2011-09-21 | — | — | EP | disclosed |
| EP-2316828-A1 | Piperazine derivatives and their use as therapeutic agents | Xenon Pharmaceuticals Inc. (CA) | 2011-05-04 | — | — | EP | disclosed |
| US-7919484-B2 | Combination therapy | XENON PHARMACEUTICALS INC. (CA) | 2011-04-05 | — | — | US | disclosed |