Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | HPGDS | O60760 | 3/20 | 0.31 |
| ▸ | TTK | P33981 | 4/20 | 0.31 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16577431 | 0.99 | MAPK13 (0.38) | MAPK13MAPK12MAPK11MAPK14SCN10A | |
| SCHEMBL15586688 | 0.99 | MAPK13 (0.38) | MAPK13MAPK12MAPK11MAPK14SCN10A | |
| SCHEMBL15586250 | 0.96 | MAPK13 (0.36) | MAPK13MAPK12MAPK11MAPK14SCN10A | |
| SCHEMBL18506163 | 0.91 | MAPK13 (0.35) | MAPK13MAPK12MAPK11MAPK14SCN10A | |
| SCHEMBL15586479 | 0.87 | MAPK13 (0.38) | MAPK13MAPK12MAPK11MAPK14SCN10A | |
| SCHEMBL16577457 | 0.85 | SSTR3 (0.34) | MAPK13MAPK12MAPK11MAPK14SCN10A | |
| SCHEMBL14793215 | 0.83 | MAPK13 (0.45) | MAPK13MAPK12MAPK11MAPK14SCN10A | |
| SCHEMBL12531125 | 0.83 | MAPK13 (0.45) | MAPK13MAPK12MAPK11MAPK14SCN10A | |
| SCHEMBL18501422 | 0.83 | SCN10A (0.35) | MAPK13MAPK12MAPK11MAPK14SCN10A | |
| SCHEMBL16948485 | 0.82 | SCN10A (0.34) | MAPK13MAPK12MAPK11MAPK14SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014131315-A1 | BRIDGED RING COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2014-09-04 | — | — | WO | disclosed |