Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 1.00 |
| ▸ | LCK | P06239 | 1/20 | 1.00 |
| ▸ | SRC | P12931 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tak-020 SCHEMBL16008415 | 1.00 | BTK (1.00) | BTKLCKSRC | |
| Tak-020 SCHEMBL16008417 | 1.00 | BTK (1.00) | BTKLCKSRC | |
| Tak-020 SCHEMBL29369338 | 1.00 | BTK (1.00) | BTKLCKSRC | |
| SCHEMBL16008567 | 0.96 | BTK (1.00) | BTKLCKSRC | |
| SCHEMBL16008564 | 0.96 | BTK (1.00) | BTKLCKSRC | |
| SCHEMBL16008158 | 0.90 | BTK (1.00) | BTKLCKSRC | |
| SCHEMBL16008153 | 0.90 | BTK (1.00) | BTKLCKSRC | |
| SCHEMBL16008157 | 0.90 | BTK (1.00) | BTKLCKSRC | |
| SCHEMBL16008155 | 0.90 | BTK (1.00) | BTKLCKSRC | |
| SCHEMBL16016706 | 0.90 | BTK (1.00) | BTKLCKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11786608-B2 | Isoquinolinyl triazolone complexes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-17 | — | — | US | claimed |
| CN-109071496-B | Isoquinolinyl triazolone complexes | 武田药品有限公司 | 2021-07-30 | — | — | CN | claimed |
| EP-3436447-B1 | ISOQUINOLINYL TRIAZOLONE COMPLEXES | TAKEDA PHARMACEUTICALS CO (JP) | 2021-07-14 | — | — | EP | claimed |
| US-20210138086-A1 | ISOQUINOLINYL TRIAZOLONE COMPLEXES | CHEN RONGLIANG (US) | 2021-05-13 | — | — | US | claimed |
| US-20190224190-A1 | PYRIDINYL AND FUSED PYRIDINYL TRIAZOLONE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-07-25 | — | — | US | claimed |
| US-20190105407-A1 | ISOQUINOLINYL TRIAZOLONE COMPLEXES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-04-11 | — | — | US | claimed |
| EP-3436447-A1 | ISOQUINOLINYL TRIAZOLONE COMPLEXES | Takeda Pharmaceutical Company Limited (JP) | 2019-02-06 | — | — | EP | claimed |
| US-9801872-B2 | Pyridinyl and fused pyridinyl triazolone derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-10-31 | — | — | US | claimed |
| WO-2017173111-A1 | ISOQUINOLINYL TRIAZOLONE COMPLEXES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-10-05 | — | — | WO | claimed |
| EP-2970202-B1 | PYRIDINYL AND FUSED PYRIDINYL TRIAZOLONE DERIVATIVES | TAKEDA PHARMACEUTICALS CO (JP) | 2017-02-01 | — | — | EP | claimed |
| US-20160310483-A1 | PYRIDINYL AND FUSED PYRIDINYL TRIAZOLONE DERIVATIVES | TAKEDA CALIFORNIA INC. | 2016-10-27 | — | — | US | claimed |
| US-9402841-B2 | Pyridinyl and fused pyridinyl triazolone derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-08-02 | — | — | US | claimed |
| US-20140256734-A1 | PYRIDINYL AND FUSED PYRIDINYL TRIAZOLONE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-09-11 | — | — | US | claimed |
| US-11786608-B2 | Isoquinolinyl triazolone complexes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-17 | — | — | US | disclosed |
| US-11786608-B2 | Isoquinolinyl triazolone complexes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-17 | — | — | US | disclosed |
| US-11786608-B2 | Isoquinolinyl triazolone complexes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-17 | — | — | US | disclosed |
| WO-2014164558-A1 | PYRIDINYL AND FUSED PYRIDINYL TRIAZOLONE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-10-09 | — | — | WO | disclosed |
| US-20140256734-A1 | PYRIDINYL AND FUSED PYRIDINYL TRIAZOLONE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-09-11 | — | — | US | disclosed |
| US-20140256734-A1 | PYRIDINYL AND FUSED PYRIDINYL TRIAZOLONE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-09-11 | — | — | US | disclosed |
| US-20140256734-A1 | PYRIDINYL AND FUSED PYRIDINYL TRIAZOLONE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190105407-A1 | ISOQUINOLINYL TRIAZOLONE COMPLEXES | BTK, LCK, TYK2 | BTK 1/4885LCK 2/4885SRC 44/4885 |
| US-20160310483-A1 | PYRIDINYL AND FUSED PYRIDINYL TRIAZOLONE DERIVATIVES | BTK, LCK, TYK2 | BTK 1/4885LCK 2/4885SRC 168/4885 |
| US-11786608-B2 | Isoquinolinyl triazolone complexes | BTK, LCK, SYK | BTK 1/4885LCK 2/4885SRC 32/4885 |
| US-20210138086-A1 | ISOQUINOLINYL TRIAZOLONE COMPLEXES | BTK, LCK, SYK | BTK 1/4885LCK 2/4885SRC 32/4885 |
| US-20190224190-A1 | PYRIDINYL AND FUSED PYRIDINYL TRIAZOLONE DERIVATIVES | BTK, LCK, TYK2 | BTK 1/4885LCK 2/4885SRC 168/4885 |
| US-20140256734-A1 | PYRIDINYL AND FUSED PYRIDINYL TRIAZOLONE DERIVATIVES | BTK, LCK, TYK2 | BTK 1/4885LCK 2/4885SRC 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.