Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16011884 | 1.00 | ATM (0.34) | ATMRENCMA1HDAC8CTSL | |
| SCHEMBL17364144 | 0.93 | PEPD (0.36) | RENHDAC8CTSLCTSBCTSK | |
| SCHEMBL16012130 | 0.93 | PEPD (0.36) | RENHDAC8CTSLCTSBCTSK | |
| SCHEMBL13830154 | 0.91 | ATM (0.35) | ATMRENCMA1HDAC8CTSL | |
| SCHEMBL15647847 | 0.91 | ATM (0.35) | ATMRENCMA1HDAC8CTSL | |
| SCHEMBL19458006 | 0.89 | ATM (0.37) | ATMCMA1HDAC8CTSLCTSB | |
| SCHEMBL13729666 | 0.89 | ATM (0.37) | ATMCMA1HDAC8CTSLCTSB | |
| SCHEMBL13728313 | 0.89 | ATM (0.37) | ATMCMA1HDAC8CTSLCTSB | |
| SCHEMBL15668594 | 0.89 | ATM (0.37) | ATMCMA1HDAC8CTSLCTSB | |
| SCHEMBL17732635 | 0.89 | ATM (0.37) | ATMCMA1HDAC8CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964664-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2016-01-13 | — | — | EP | disclosed |
| WO-2014137869-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-09-12 | — | — | WO | disclosed |