Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 4/20 | 0.39 |
| ▸ | ARG1 | P05089 | 1/20 | 0.39 |
| ▸ | ARG2 | P78540 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12348733 | 1.00 | PRCP (0.46) | PRCPDPP7HTR2CHTR2BSCN4A | |
| SCHEMBL3669478 | 0.84 | SCN4A (0.47) | PRCPDPP7HTR2CHTR2BSCN4A | |
| SCHEMBL17676964 | 0.84 | SCN4A (0.47) | PRCPDPP7HTR2CHTR2BSCN4A | |
| SCHEMBL3333289 | 0.84 | SCN4A (0.47) | PRCPDPP7HTR2CHTR2BSCN4A | |
| SCHEMBL9825084 | 0.82 | EPHX1 (0.48) | PRCPDPP7HTR2CHTR2BSCN4A | |
| SCHEMBL7265700 | 0.82 | EPHX1 (0.48) | PRCPDPP7HTR2CHTR2BSCN4A | |
| SCHEMBL5157107 | 0.82 | EPHX1 (0.48) | PRCPDPP7HTR2CHTR2BSCN4A | |
| SCHEMBL17676973 | 0.82 | EPHX1 (0.48) | PRCPDPP7HTR2CHTR2BSCN4A | |
| SCHEMBL3330098 | 0.82 | SCN4A (0.48) | PRCPDPP7HTR2CHTR2BSCN4A | |
| SCHEMBL3332602 | 0.82 | SCN4A (0.48) | PRCPDPP7HTR2CHTR2BSCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8829208-B2 | Process for the preparation of darunavir and darunavir intermediates | MAPI PHARMA LTD. (IL) | 2014-09-09 | — | — | US | disclosed |
| US-8829208-B2 | Process for the preparation of darunavir and darunavir intermediates | MAPI PHARMA LTD. (IL) | 2014-09-09 | — | — | US | disclosed |