Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | STAT1 | P42224 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2687005 | 0.90 | KDM4E (0.47) | NPC1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL10219624 | 0.89 | NPC1 (0.49) | NPC1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2686319 | 0.88 | NPC1 (0.48) | NPC1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2686523 | 0.87 | KDM4E (0.48) | NPC1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2687098 | 0.87 | KDM4E (0.45) | NPC1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2688624 | 0.86 | KMT2A (0.53) | NPC1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2688713 | 0.86 | NPC1 (0.44) | NPC1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2687383 | 0.85 | KDM4E (0.55) | NPC1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2686969 | 0.84 | NPC1 (0.47) | NPC1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2687577 | 0.84 | MEN1 (0.47) | NPC1KDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8829035-B2 | Agent for treatment or prevention of diseases associated with activity of neurotrophic factors | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-09-09 | — | — | US | disclosed |