⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1391357 | 0.81 | — | — | |
| SCHEMBL10087269 | 0.80 | — | — | |
| SCHEMBL13805531 | 0.77 | ODC1 (0.31) | — | |
| SCHEMBL19890099 | 0.76 | HSD17B10 (0.31) | — | |
| SCHEMBL12767708 | 0.76 | HSD17B10 (0.31) | — | |
| SCHEMBL416419 | 0.75 | — | — | |
| SCHEMBL285592 | 0.75 | TSHR (0.30) | — | |
| SCHEMBL12731238 | 0.74 | HSD17B10 (0.30) | — | |
| SCHEMBL19930034 | 0.74 | TSHR (0.32) | — | |
| Hydrochloric Acid SCHEMBL2951043 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230279041-A1 | FUNCTIONALIZED N-ACETYLGALACTOSAMINE ANALOGS | HONGENE BIOTECH CORPORATION | 2023-09-07 | — | — | US | disclosed |
| US-20230016929-A1 | EXTRAHEPATIC DELIVERY | BANK OF AMERICA, N.A. | 2023-01-19 | — | — | US | disclosed |
| US-10953105-B2 | Immunostimulatory compositions and methods of use thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-03-23 | — | — | US | disclosed |
| US-20190015522-A1 | IMMUNOSTIMULATORY COMPOSITIONS AND METHODS OF USE THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2019-01-17 | — | — | US | disclosed |
| US-20160348110-A1 | NUCLEIC ACID CHEMICAL MODIFICATIONS | ALNYLAM PHARMACEUTICALS INC (US) | 2016-12-01 | — | — | US | disclosed |
| US-9345780-B2 | Site specific delivery of nucleic acids by combining targeting ligands with endosomolytic components | TEKMIRA PHARMACEUTICALS CORPORATION (CA) | 2016-05-24 | — | — | US | disclosed |
| US-9090648-B2 | Cationic oligonucleotides, automated methods for preparing same and their uses | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2015-07-28 | — | — | US | disclosed |
| US-20140256785-A1 | SITE SPECIFIC DELIVERY OF NUCLEIC ACIDS BY COMBINING TARGETING LIGANDS WITH ENDOSOMOLYTIC COMPONENTS | TEKMIRA PHARMACEUTICALS CORPORATION (CA) | 2014-09-11 | — | — | US | disclosed |