Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 9/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.64 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CNR1 | P21554 | 1/20 | 0.64 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | PGR | P06401 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.59 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.59 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.59 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.59 |
| ▸ | HRH1 | P35367 | 1/20 | 0.59 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16018300 | 1.00 | HIF1A (0.65) | HIF1ALMNACYP3A4NR3C1CYP2C9 | |
| SCHEMBL16018298 | 0.99 | HIF1A (0.66) | HIF1ALMNACYP3A4NR3C1CYP2C9 | |
| SCHEMBL16018299 | 0.98 | HIF1A (0.62) | HIF1ALMNACYP3A4NR3C1CYP2C9 | |
| SCHEMBL16018295 | 0.98 | HIF1A (0.62) | HIF1ALMNACYP3A4NR3C1CYP2C9 | |
| SCHEMBL16018294 | 0.96 | HIF1A (0.64) | HIF1ALMNACYP3A4NR3C1CYP2C9 | |
| SCHEMBL16018297 | 0.96 | HIF1A (0.64) | HIF1ALMNACYP3A4NR3C1CYP2C9 | |
| SCHEMBL16020593 | 0.95 | HIF1A (0.62) | HIF1ALMNACYP3A4NR3C1CYP2C9 | |
| SCHEMBL16018305 | 0.95 | HIF1A (0.62) | HIF1ALMNACYP3A4NR3C1CYP2C9 | |
| SCHEMBL16007329 | 0.95 | HIF1A (0.62) | HIF1ALMNACYP3A4NR3C1CYP2C9 | |
| SCHEMBL16007204 | 0.95 | HIF1A (0.62) | HIF1ALMNACYP3A4NR3C1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014138437-A1 | STEROID CONJUGATES | ALLERGAN, INC. (US) | 2014-09-12 | — | — | WO | disclosed |
| US-20140256696-A1 | Steroid conjugates | ALLERGAN, INC. (US) | 2014-09-11 | — | — | US | disclosed |
| US-20140256696-A1 | Steroid conjugates | ALLERGAN, INC. (US) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256696-A1 | Steroid conjugates | CYP21A2, CYP17A1, HSD17B2 | HIF1A 4514/4885LMNA 3852/4885CYP3A4 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.