SCHEMBL1602174

SCHEMBL1602174

COC(Br)Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31296304 0.74
SCHEMBL11436191 0.74
SCHEMBL22118875 0.74
SCHEMBL5404 0.74
SCHEMBL8033634 0.70
SCHEMBL8861364 0.70
SCHEMBL6915362 0.70
SCHEMBL30901457 0.70
SCHEMBL11159232 0.67
SCHEMBL11033461 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117886790-B CochlearolB synthesis method 陕西师范大学 2025-10-28 CN disclosed
CN-117886790-A Synthesis method of CochlearolB 陕西师范大学 2024-04-16 CN disclosed
CN-117886790-A Synthesis method of CochlearolB 陕西师范大学 2024-04-16 CN disclosed
CN-116217584-A Method for photocatalytic synthesis of ET743 and intermediates thereof 南通诺泰生物医药技术有限公司 2023-06-06 CN disclosed
CN-114349633-A Process for the preparation of diesters of glutaconic acid 华烁科技股份有限公司 2022-04-15 CN disclosed
CN-108358783-B 3-substituted glutaric diester and preparation method of glutaconic diester 华烁科技股份有限公司 2021-04-06 CN disclosed
EP-2997020-A1 PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLIC ACID COMPOUNDS AND DERIVATIVES THEREOF BASF SE (DE) 2016-03-23 EP disclosed
US-20150036276-A1 TRANSPARENT CONDUCTIVE FILM, CONDUCTIVE ELEMENT, COMPOSITION, COLORED SELF-ASSEMBLED MATERIAL, INPUT DEVICE, DISPLAY DEVICE, AND ELECTRONIC INSTRUMENT DEXERIALS CORPORATION (JP) 2015-02-05 US disclosed
WO-2014184343-A1 PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLIC ACID COMPOUNDS AND DERIVATIVES THEREOF BASF SE (DE) 2014-11-20 WO disclosed
EP-1521762-B1 PROCESSES FOR THE PRODUCTION OF AMINOALKYL GLUCOSAMINIDE PHOSPHATE AND DISACCHARIDE IMMUNOEFFECTORS, AND INTERMEDIATES THEREFOR CORIXA CORP (US) 2014-03-12 EP disclosed
EP-1185536-A2 HEMISYNTHETIC METHOD AND INTERMEDIATES THEREOF PHARMA MAR, S.A. (ES) 2002-03-13 EP disclosed
WO-2001087894-A1 ANTITUMORAL ANALOGS OF ET-743 PHARMA MAR, S.A. (ES) 2001-11-22 WO disclosed
WO-2001087895-A1 SYNTHETIC PROCESS FOR THE MANUFACTURE OF AN ECTEINASCHIDIN COMPOUND PHARMA MAR, S.A. (ES) 2001-11-22 WO disclosed
WO-2001077115-A1 ANTITUMORAL ECTEINASCIDIN DERIVATIVES PHARMA MAR, S.A. (ES) 2001-10-18 WO disclosed
WO-2000069862-A2 HEMISYNTHETIC METHOD AND INTERMEDIATES THEREOF PHARMA MAR, S.A. (ES) 2000-11-23 WO disclosed
US-5886211-A Process for producing 2-(halomethyl)phenylacetic acid esters SAGAMI CHEMICAL RESEARCH CENTER (JP) 1999-03-23 US disclosed
EP-0834497-A1 PROCESS FOR PRODUCING 2-(HALOMETHYL)PHENYLACETIC ACID ESTERS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1998-04-08 EP disclosed
EP-0058945-B1 A PROCESS FOR PREPARING AN OPTICALLY ACTIVE D-ALPHA-TOCOPHEROL AND COMPOUNDS FOR ITS PREPARATION Eisai Co., Ltd. (JP) 1986-08-13 EP disclosed
US-4433159-A Synthesis of optically active d-alpha tocopherol EISAI CO., LTD. (JP) 1984-02-21 US disclosed
EP-0058945-A2 A process for preparing an optically active d-alpha-tocopherol and compounds for its preparation Eisai Co., Ltd. (JP) 1982-09-01 EP disclosed