Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 17/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16022399 | 0.97 | PDK2 (0.37) | PDK2CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL16022413 | 0.91 | PDK2 (0.33) | PDK2CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL16025158 | 0.89 | PDK2 (0.36) | PDK2APEX1CRHBPCRHR2KEAP1 | |
| SCHEMBL16022391 | 0.88 | PDK2 (0.36) | PDK2APEX1 | |
| SCHEMBL16017945 | 0.87 | PDK2 (0.34) | PDK2APEX1 | |
| SCHEMBL16017969 | 0.87 | PDK2 (0.42) | PDK2CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL16025161 | 0.86 | PDK2 (0.36) | PDK2CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL16022393 | 0.85 | PDK2 (0.35) | PDK2 | |
| SCHEMBL16017913 | 0.85 | PDK2 (0.39) | PDK2APEX1 | |
| SCHEMBL16025184 | 0.83 | PDK2 (0.39) | PDK2APEX1CRHBPCRHR2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9316931-B2 | Electrophotographic photosensitive member, electrophotographic apparatus, process cartridge, and condensed polycyclic aromatic compound | CANON KABUSHIKI KAISHA (JP) | 2016-04-19 | — | — | US | disclosed |
| US-20140255836-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND ELECTROPHOTOGRAPHIC APPARATUS AND PROCESS CARTRIDGE EACH INCLUDING THE ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | CANON KABUSHIKI KAISHA (JP) | 2014-09-11 | — | — | US | disclosed |