Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 3/20 | 0.48 |
| ▸ | CDK2 | P24941 | 3/20 | 0.48 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 12/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 12/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 9/20 | 0.42 |
| ▸ | CDK1 | P06493 | 9/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 9/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 9/20 | 0.42 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2359928 | 0.92 | CCNE2 (0.55) | CCNE1CDK2CCNE2CDK5CDK5R1 | |
| SCHEMBL2359975 | 0.91 | CCNE1 (0.46) | CCNE1CDK2CCNE2CDK5CDK5R1 | |
| SCHEMBL2359895 | 0.90 | CDK2 (0.47) | CCNE1CDK2CCNE2CDK5CDK5R1 | |
| SCHEMBL21253888 | 0.90 | CCNE1 (0.46) | CCNE1CDK2CCNE2CDK5CDK5R1 | |
| SCHEMBL2314426 | 0.89 | CCNE1 (0.46) | CCNE1CDK2CCNE2CDK5CDK5R1 | |
| SCHEMBL21240843 | 0.89 | CCNE2 (0.61) | CCNE1CDK2CCNE2CDK5CDK5R1 | |
| SCHEMBL2357127 | 0.88 | CCNE1 (0.45) | CCNE1CDK2CCNE2CDK5CDK5R1 | |
| SCHEMBL2358698 | 0.87 | CCNE2 (0.56) | CCNE1CDK2CCNE2CDK5CDK5R1 | |
| SCHEMBL2358532 | 0.87 | CCNE2 (0.54) | CCNE1CDK2CCNE2MEN1USP2 | |
| SCHEMBL21754215 | 0.87 | CDK2 (0.46) | CCNE1CDK2CCNE2CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014138485-A1 | EX VIVO PRODUCTION OF PLATELETS FROM HEMATOPOIETIC STEM CELLS AND THE PRODUCT THEREOF | IRM LLC (BM) | 2014-09-12 | — | — | WO | disclosed |