Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16013697 | 0.89 | BTK (1.00) | BTKCLK2 | |
| SCHEMBL16014706 | 0.89 | BTK (1.00) | BTKCLK2 | |
| SCHEMBL18895727 | 0.88 | BTK (0.81) | BTKCLK2 | |
| SCHEMBL16013281 | 0.88 | BTK (1.00) | BTKCLK2 | |
| SCHEMBL3205568 | 0.85 | BTK (0.78) | BTKCLK2 | |
| SCHEMBL1724202 | 0.85 | BTK (0.84) | BTKCLK2 | |
| SCHEMBL9985437 | 0.83 | BTK (0.79) | BTKCLK2 | |
| SCHEMBL15577291 | 0.82 | BTK (0.81) | BTKCLK2 | |
| SCHEMBL19593991 | 0.81 | BTK (0.86) | BTKCLK2 | |
| SCHEMBL19594126 | 0.81 | BTK (0.85) | BTKCLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014135474-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | F. HOFFMANN-LA ROCHE AG (CH) | 2014-09-12 | — | — | WO | disclosed |