Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SQLE | Q14534 | 4/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1191493 | 0.73 | TSHR (0.52) | TSHRKMT2ASQLEALOX15MAPT | |
| SCHEMBL15709505 | 0.71 | TSHR (0.54) | TSHRKMT2ASQLEALOX15MAPT | |
| SCHEMBL7561754 | 0.71 | TSHR (0.45) | TSHRKMT2ASQLEALOX15MAPT | |
| SCHEMBL20171227 | 0.71 | KMT2A (0.61) | KMT2ASQLEALOX15MAPTMEN1 | |
| SCHEMBL7568956 | 0.70 | TSHR (0.48) | TSHRKMT2ASQLEALOX15MAPT | |
| SCHEMBL1982504 | 0.70 | TSHR (0.48) | TSHRKMT2ASQLEALOX15MAPT | |
| SCHEMBL17429481 | 0.69 | TSHR (0.40) | TSHRKMT2ASQLEALOX15MAPT | |
| SCHEMBL7561867 | 0.69 | KMT2A (0.53) | KMT2ASQLEALOX15MAPTMEN1 | |
| SCHEMBL7583169 | 0.69 | KMT2A (0.53) | KMT2ASQLEALOX15MAPTMEN1 | |
| SCHEMBL7583163 | 0.69 | KMT2A (0.53) | KMT2ASQLEALOX15MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014138113-A2 | 1,2-HYDROSILYLATION OF DIENES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-09-12 | — | — | WO | disclosed |