SCHEMBL1602956

SCHEMBL1602956

CCCCCCC=C(C#N)C(=O)OC(=O)C(C#N)=CCCCCCCCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.46
PPARG P37231 7/20 0.39
PPARA Q07869 2/20 0.39
TRPA1 O75762 1/20 0.39
FBP1 P09467 1/20 0.39
FAAH O00519 2/20 0.38
LMNA P02545 2/20 0.38
POLB P06746 2/20 0.38
MAPT P10636 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
MEN1 O00255 1/20 0.38
CYP3A4 P08684 1/20 0.38
GAA P10253 1/20 0.38
CYP2D6 P10635 1/20 0.38
KMT2A Q03164 1/20 0.38
GMNN O75496 1/20 0.37
USP2 O75604 1/20 0.37
CYP1A2 P05177 1/20 0.37
ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6438050 0.98 EP300 (0.44) EP300PPARGPPARATRPA1FBP1
SCHEMBL20395025 0.91 TSHR (0.42) EP300PPARGPPARATRPA1FBP1
SCHEMBL28440501 0.91 TSHR (0.44) EP300PPARGPPARATRPA1FBP1
SCHEMBL1987588 0.89 EP300 (0.40) EP300PPARGPPARATRPA1FBP1
SCHEMBL1987673 0.89 EP300 (0.40) EP300PPARGPPARATRPA1FBP1
SCHEMBL27647414 0.88 EP300 (0.44) EP300PPARGPPARATRPA1FBP1
SCHEMBL19573442 0.88 EP300 (0.44) EP300PPARGPPARATRPA1FBP1
SCHEMBL1988663 0.87 EP300 (0.38) EP300PPARGPPARATRPA1FBP1
SCHEMBL8600351 0.87 CYP2C9 (0.53) EP300FAAHLMNAPOLBMAPT
SCHEMBL11208867 0.87 CYP2C9 (0.53) EP300FAAHLMNAPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1957206-B1 APPLICATOR FOR TUBE DISPENSER FOR LOW AND HIGH VISCOSITY ADHESIVE COMPONENTS CHEMENCE INC (US) 2011-06-08 EP disclosed
US-7918621-B2 Applicator and tube dispenser for low and high viscosity adhesive components Clast Trading Ltd. (HK) 2011-04-05 US disclosed
US-20090036921-A1 Controlled Viscosity Tissue Adhesive CHEMENCE (US) 2009-02-05 US disclosed
EP-1957206-A1 APPLICATOR AND TUBE DISPENSER FOR LOW AND HIGH VISCOSITY ADHESIVE COMPONENTS Chemence, Inc. (US) 2008-08-20 EP disclosed
WO-2007070420-A1 APPLICATOR AND TUBE DISPENSER FOR LOW AND HIGH VISCOSITY ADHESIVE COMPONENTS CHEMENCE INC. (US) 2007-06-21 WO disclosed
US-20070131356-A1 Applicator and tube dispenser for low and high viscosity adhesive components CLAST TRADING LTD (HK) 2007-06-14 US disclosed
EP-1779314-A2 CONTROLLED VISCOSITY TISSUE ADHESIVE Chemence, Inc. (US) 2007-05-02 EP disclosed
WO-2006023605-A2 CONTROLLED VISCOSITY TISSUE ADHESIVE CHEMENCE INC. (US) 2006-03-02 WO disclosed
US-20050245966-A1 Controlled viscosity tissue adhesive CLAST TRADING LTD (HK) 2005-11-03 US disclosed