⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1603345 | 0.95 | — | — | |
| SCHEMBL1603252 | 0.95 | — | — | |
| SCHEMBL1603047 | 0.95 | — | — | |
| SCHEMBL2847937 | 0.84 | — | — | |
| SCHEMBL17459903 | 0.79 | — | — | |
| SCHEMBL587850 | 0.79 | — | — | |
| SCHEMBL6227475 | 0.78 | — | — | |
| SCHEMBL4584235 | 0.76 | — | — | |
| SCHEMBL10859923 | 0.72 | — | — | |
| SCHEMBL3432761 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102170784-A | Treatment of hepatitis C infection with metalloporphyrins | CHARLOTTE MECKLENBURG HOSPITAL | 2011-08-31 | — | — | CN | claimed |
| EP-2348848-A1 | TREATMENT OF HEPATITIS C INFECTION WITH METALLOPORPHYRINS | Charlotte-Mecklenburg Hospital Authority doing business as Carolinas Medical Center (US) | 2011-08-03 | — | — | EP | claimed |
| WO-2010040063-A1 | TREATMENT OF HEPATITIS C INFECTION WITH METALLOPORPHYRINS | THE CHARLOTTE-MECKLENBURG HOSPITAL AUTHORITY D/B/A CAROLINAS MEDICAL CENTER (US) | 2010-04-08 | — | — | WO | claimed |
| US-20100086519-A1 | Treatment of Hepatitis C Infection With Metalloporphyrins | THE CHARLOTTE-MECKLENBURG HOSPITAL AUTHORITY D/B/A CAROLINAS MEDICAL CENTER | 2010-04-08 | — | — | US | claimed |
| US-11078220-B2 | High-purity large-scale preparation of stannsoporfin | Mallinckrodt Hospital Products IP Limited (IE) | 2021-08-03 | — | — | US | disclosed |
| US-20200255458-A1 | HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN | MALLINCKRODT LLC | 2020-08-13 | — | — | US | disclosed |
| US-10662209-B2 | High-purity large-scale preparation of stannsoporfin | Mallinckrodt Hospital Products IP Limited (IE) | 2020-05-26 | — | — | US | disclosed |
| US-20190202846-A1 | HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN | SpecGx LLC | 2019-07-04 | — | — | US | disclosed |
| US-10273255-B2 | High-purity large-scale preparation of stannsoporfin | INFACARE PHARMACEUTICAL CORPORATION (US) | 2019-04-30 | — | — | US | disclosed |
| CN-104116745-B | composition comprising stannsoporfin | 婴儿护理药品公司 | 2018-07-06 | — | — | CN | disclosed |
| US-20180134735-A1 | HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN | MALLINCKRODT LLC | 2018-05-17 | — | — | US | disclosed |
| US-9902745-B2 | High-purity large-scale preparation of stannsoporfin | INFACARE PHARMACEUTICAL CORPORATION (US) | 2018-02-27 | — | — | US | disclosed |
| EP-2384756-A2 | High-purity large-scale preparation of stannsoporfin | InfaCare Pharmaceutical Corporation (US) | 2011-11-09 | — | — | EP | disclosed |
| CN-102170784-A | Treatment of hepatitis C infection with metalloporphyrins | CHARLOTTE MECKLENBURG HOSPITAL | 2011-08-31 | — | — | CN | disclosed |
| EP-2348848-A1 | TREATMENT OF HEPATITIS C INFECTION WITH METALLOPORPHYRINS | Charlotte-Mecklenburg Hospital Authority doing business as Carolinas Medical Center (US) | 2011-08-03 | — | — | EP | disclosed |
| US-7960371-B2 | reduction of hemin with hydrogenation catalysts, in the presence of hydrogen, then heating to remove iron and form mesoporphyrin, and reacting with tin oxide top form pure tin mesoporphyrin; inhibitor of heme oxygenase, used in the treatment of infant jaundice or hyperbilirubinemia; liver disorders | INFACARE PHARMACEUTICAL CORPORATION (US) | 2011-06-14 | — | — | US | disclosed |
| US-20110082292-A1 | HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN | OCERA THERAPEUTICS LLC | 2011-04-07 | — | — | US | disclosed |
| US-20100086519-A1 | Treatment of Hepatitis C Infection With Metalloporphyrins | THE CHARLOTTE-MECKLENBURG HOSPITAL AUTHORITY D/B/A CAROLINAS MEDICAL CENTER | 2010-04-08 | — | — | US | disclosed |
| WO-2010040063-A1 | TREATMENT OF HEPATITIS C INFECTION WITH METALLOPORPHYRINS | THE CHARLOTTE-MECKLENBURG HOSPITAL AUTHORITY D/B/A CAROLINAS MEDICAL CENTER (US) | 2010-04-08 | — | — | WO | disclosed |
| US-20080125585-A1 | HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN | STRATATECH CORPORATION | 2008-05-29 | — | — | US | disclosed |