SCHEMBL1604320

SCHEMBL1604320

OP(=S)(OCc1ccccc1)Oc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.53
SRC P12931 2/20 0.45
ANPEP P15144 1/20 0.42
LAP3 P28838 1/20 0.42
CETP P11597 3/20 0.41
CYP2C19 P33261 2/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
PTGS1 P23219 1/20 0.40
SLC6A2 P23975 1/20 0.40
PTGS2 P35354 1/20 0.40
SLC6A3 Q01959 1/20 0.40
HIF1A Q16665 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
CYP2C9 P11712 1/20 0.40
NR4A1 P22736 1/20 0.40
NR4A2 P43354 1/20 0.40
NR4A3 Q92570 1/20 0.40
MEN1 O00255 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1491990 0.86 TSHR (0.63) TSHRSRCCETPCYP2C19LMNA
SCHEMBL483025 0.84 SRC (0.58) TSHRSRCANPEPLAP3CYP2C19
SCHEMBL3077577 0.82 TSHR (0.59) TSHRSRCCETPCYP2C19LMNA
SCHEMBL7270129 0.82 SRC (0.56) TSHRSRCANPEPLAP3CYP2C19
Ammonia Solution, Strong SCHEMBL11664408 0.82 SRC (0.56) TSHRSRCANPEPLAP3CYP2C19
SCHEMBL3067248 0.79 TSHR (0.55) TSHRSRCCETPCYP2C19LMNA
SCHEMBL390090 0.79 SRC (0.45) TSHRSRCANPEPLAP3CYP2C19
SCHEMBL3068400 0.78 TSHR (0.63) TSHRSRCCETPCYP2C19LMNA
SCHEMBL444558 0.78 TSHR (0.75) TSHRSRCANPEPLAP3CETP
Hydrochloric Acid SCHEMBL28976264 0.76 TSHR (0.72) TSHRSRCANPEPLAP3CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760952-B2 Lubricant thickener systems from modified tall oil fatty acids, lubricating compositions, and associated methods INGEVITY SOUTH CAROLINA, LLC (US) 2023-09-19 US disclosed
US-20230097718-A1 BIOBASED EXTREME PRESSURE ADDITIVE FOR LUBRICATING COMPOSITIONS AND ASSOCIATED METHODS INGEVITY SOUTH CAROLINA, LLC 2023-03-30 US disclosed
US-20220220408-A1 LUBRICANT THICKENER SYSTEMS FROM MODIFIED TALL OIL FATTY ACIDS, LUBRICATING COMPOSITIONS, AND ASSOCIATED METHODS MAINSTREAM PINE PRODUCTS, LLC 2022-07-14 US disclosed
EP-3562924-B1 LOW VISCOSITY LUBRICATING OIL COMPOSITIONS FOR TURBOMACHINES EXXONMOBIL RES & ENG CO (US) 2022-05-25 EP disclosed
US-10774286-B2 Grease compositions with improved performance and methods of preparing and using the same EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-09-15 US disclosed
EP-3684895-A1 HYDRAULIC OIL COMPOSITIONS WITH IMPROVED HYDROLYTIC AND THERMO-OXIDATIVE STABILITY ExxonMobil Research and Engineering Company (US) 2020-07-29 EP disclosed
WO-2020131440-A1 GREASE COMPOSITIONS HAVING CALCIUM SULFONATE AND POLYUREA THICKENERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-06-25 WO disclosed
WO-2020131441-A1 GREASE COMPOSITIONS HAVING IMPROVED PERFORMANCE EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-06-25 WO disclosed
US-20200199473-A1 GREASE COMPOSITIONS HAVING IMPROVED PERFORMANCE EXXONMOBIL RES & ENG CO (US) 2020-06-25 US disclosed
US-20200199481-A1 GREASE COMPOSITIONS HAVING CALCIUM SULFONATE AND POLYUREA THICKENERS EXXONMOBIL RES & ENG CO (US) 2020-06-25 US disclosed
EP-2038385-A1 NOVEL BASE STOCK LUBRICANT BLENDS ExxonMobil Research and Engineering Company (US) 2009-03-25 EP disclosed
US-20080207475-A1 High viscosity novel base stock lubricant viscosity blends HAIGH HEATHER M 2008-08-28 US disclosed
US-20080020954-A1 High viscosity novel base stock lubricant extreme viscosity blends HAIGH HEATHER M 2008-01-24 US disclosed
US-20070298990-A1 High viscosity metallocene catalyst pao novel base stock lubricant blends EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2007-12-27 US disclosed
WO-2007146081-A1 HIGH VISCOSITY NOVEL BASE STOCK LUBRICANT EXTREME VISCOSITY BLENDS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-12-21 WO disclosed
WO-2007145923-A1 NOVEL BASE STOCK LUBRICANT BLENDS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-12-21 WO disclosed
WO-2007145924-A1 HIGH VISCOSITY METALLOCENE CATALYST PAO NOVEL BASE STOCK LUBRICANT BLENDS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-12-21 WO disclosed
US-20070289897-A1 Novel base stock lubricant blends CAREY JAMES T 2007-12-20 US disclosed
US-20020010103-A1 Lubricating oil composition having excellent thermal stability, extreme pressure resistance and anti-wear performance CHEVRON ORONITE JAPAN LIMITED (JP) 2002-01-24 US disclosed
EP-1148114-A2 Lubricating oil compositions having excellent thermal stabilty, extreme pressure resistance and anti-wear performance Chevron Oronite Japan Limited (JP) 2001-10-24 EP disclosed