SCHEMBL16047435

SCHEMBL16047435

CCCCCCCC[CH]CC(Cl)Cl

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.42
THRB P10828 1/20 0.38
FAAH O00519 3/20 0.38
TRPV1 Q8NER1 1/20 0.38
DNM1 Q05193 3/20 0.36
ALDH1A1 P00352 1/20 0.36
EP300 Q09472 1/20 0.34
MEN1 O00255 1/20 0.34
CYP3A4 P08684 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6242253 0.78 TSHR (0.44) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL9784627 0.78 TSHR (0.44) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL3855699 0.78 TSHR (0.44) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL29262877 0.76 MEN1 (0.42) TSHRTHRBFAAHTRPV1ALDH1A1
SCHEMBL28100039 0.76 TSHR (0.42) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL29229626 0.76 MEN1 (0.42) TSHRTHRBFAAHTRPV1ALDH1A1
SCHEMBL25171010 0.76 TSHR (0.58) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL25174128 0.76 TSHR (0.58) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL25170219 0.76 TSHR (0.58) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL25171009 0.76 TSHR (0.58) TSHRTHRBFAAHTRPV1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240084343-A1 METHODS OF USING NATURAL AND ENGINEERED ORGANISMS TO PRODUCE SMALL MOLECULES FOR INDUSTRIAL APPLICATION KIVERDI INC (US) 2024-03-14 US disclosed
US-20210115481-A1 Methods of Using Natural and Engineered Organisms to Produce Small Molecules for Industrial Application KIVERDI INC (US) 2021-04-22 US disclosed
US-20170159087-A1 Methods of Using Natural and Engineered Organisms to Produce Small Molecules for Industrial Application KIVERDI, INC. (US) 2017-06-08 US disclosed
US-9556462-B2 Methods of using natural and engineered organisms to produce small molecules for industrial application KIVERDI, INC. (US) 2017-01-31 US disclosed
EP-2971023-A2 METHODS OF USING NATURAL AND ENGINEERED ORGANISMS TO PRODUCE SMALL MOLECULES FOR INDUSTRIAL APPLICATION Kiverdi, Inc. (US) 2016-01-20 EP disclosed
US-20140273112-A1 METHODS OF USING NATURAL AND ENGINEERED ORGANISMS TO PRODUCE SMALL MOLECULES FOR INDUSTRIAL APPLICATION KIVERDI, INC. (US) 2014-09-18 US disclosed
WO-2014145194-A2 METHODS OF USING NATURAL AND ENGINEERED ORGANISMS TO PRODUCE SMALL MOLECULES FOR INDUSTRIAL APPLICATION KIVERDI, INC. (US) 2014-09-18 WO disclosed