Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 10/20 | 0.49 |
| ▸ | BIRC2 | Q13490 | 5/20 | 0.49 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CASP9 | P55211 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14421210 | 1.00 | XIAP (0.49) | XIAPBIRC2BIRC3CYP3A4CYP2C9 | |
| SCHEMBL15705223 | 1.00 | XIAP (0.49) | XIAPBIRC2BIRC3CYP3A4CYP2C9 | |
| SCHEMBL160497 | 1.00 | XIAP (0.49) | XIAPBIRC2BIRC3CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL156849 | 0.99 | XIAP (0.49) | XIAPBIRC2BIRC3CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL156848 | 0.99 | XIAP (0.49) | XIAPBIRC2BIRC3CYP3A4CYP2C9 | |
| SCHEMBL157183 | 0.93 | XIAP (0.43) | XIAPBIRC2BIRC3CYP3A4CYP2C9 | |
| SCHEMBL3722484 | 0.89 | BIRC2 (0.50) | XIAPBIRC2BIRC3CYP3A4CYP2C9 | |
| SCHEMBL24051779 | 0.89 | ELANE (0.42) | XIAPBIRC2BIRC3CYP3A4CYP2C9 | |
| SCHEMBL14050770 | 0.88 | BIRC2 (0.54) | XIAPBIRC2BIRC3CYP3A4CYP2C9 | |
| SCHEMBL15304272 | 0.88 | BIRC2 (0.54) | XIAPBIRC2BIRC3CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611797-A2 | QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS | Hanmi Science Co., Ltd. (KR) | 2013-07-10 | — | — | EP | claimed |
| WO-2012030160-A2 | QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS | HANMI HOLDINGS CO., LTD. (KR) | 2012-03-08 | — | — | WO | claimed |
| EP-2611797-A2 | QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS | Hanmi Science Co., Ltd. (KR) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012030160-A2 | QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS | HANMI HOLDINGS CO., LTD. (KR) | 2012-03-08 | — | — | WO | disclosed |