Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.36 |
| ▸ | MTOR | P42345 | 8/20 | 0.36 |
| ▸ | PIK3C2A | O00443 | 2/20 | 0.36 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | USP14 | P54578 | 4/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 2/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16054694 | 1.00 | RXFP1 (0.39) | RXFP1PIK3CAMTORPIK3C2APIK3C2B | |
| SCHEMBL16055241 | 0.91 | ATM (0.36) | RXFP1PIK3CAMTORPIK3C2APIK3C2B | |
| SCHEMBL16055242 | 0.91 | ATM (0.36) | RXFP1PIK3CAMTORPIK3C2APIK3C2B | |
| SCHEMBL16055020 | 0.87 | MTOR (0.43) | RXFP1PIK3CAMTORPIK3C2APIK3C2B | |
| SCHEMBL16054426 | 0.84 | RXFP1 (0.36) | RXFP1ATMMAPTUSP14MAPK1 | |
| SCHEMBL16054425 | 0.84 | RXFP1 (0.36) | RXFP1ATMMAPTUSP14MAPK1 | |
| SCHEMBL16054732 | 0.84 | MTOR (0.40) | PIK3CAMTORPIK3C2APIK3C2BATM | |
| SCHEMBL16054734 | 0.84 | MTOR (0.40) | PIK3CAMTORPIK3C2APIK3C2BATM | |
| SCHEMBL16054431 | 0.78 | RXFP1 (0.39) | RXFP1PIK3CAMTORATMMAPT | |
| SCHEMBL16054433 | 0.78 | PIK3CA (0.34) | PIK3CAMTORPIK3C2APIK3C2BATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014141118-A1 | IMIDAZO[4,5-C]QUINOLINE DERIVATIVES AND USES THEREOF | Piramal Enterprises Limited (IN) | 2014-09-18 | — | — | WO | disclosed |