Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLB1 | P16278 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14853747 | 1.00 | GLB1 (0.40) | GLB1HPGDGAAMGAMCA1 | |
| SCHEMBL16708496 | 0.84 | GLB1 (0.37) | GLB1HPGDGAAMGAMCA1 | |
| SCHEMBL12838253 | 0.80 | GLB1 (0.40) | GLB1HPGDALDH1A1 | |
| SCHEMBL19425953 | 0.80 | GLB1 (0.40) | GLB1HPGDALDH1A1 | |
| SCHEMBL12855090 | 0.80 | GLB1 (0.40) | GLB1HPGDALDH1A1 | |
| SCHEMBL20033569 | 0.80 | GLB1 (0.40) | GLB1HPGDALDH1A1 | |
| SCHEMBL17358581 | 0.80 | GLB1 (0.37) | GLB1 | |
| SCHEMBL20756353 | 0.76 | GLB1 (0.37) | GLB1 | |
| SCHEMBL16063057 | 0.74 | GLB1 (0.36) | GLB1 | |
| SCHEMBL22799644 | 0.73 | GLB1 (0.34) | GLB1GAAMGAMCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835615-B2 | 2′-fluorine-4′-substituted-nucleoside analogues, preparation methods and uses thereof | HENAN GENUINE BIOTECH CO., LTD. (CN) | 2014-09-16 | — | — | US | disclosed |