Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 15/20 | 0.63 |
| ▸ | FAP | Q12884 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 14/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16063273 | 0.89 | CYP3A4 (0.71) | CYP3A4FAPCYP2D6 | |
| SCHEMBL20460806 | 0.89 | CYP3A4 (0.71) | CYP3A4FAPCYP2D6 | |
| SCHEMBL16066010 | 0.88 | CYP3A4 (0.50) | CYP3A4FAPCYP2D6 | |
| SCHEMBL15070860 | 0.87 | CYP3A4 (0.77) | CYP3A4FAPCYP2D6 | |
| SCHEMBL19508638 | 0.87 | CYP3A4 (0.65) | CYP3A4FAPCYP2D6 | |
| SCHEMBL20644398 | 0.86 | CYP3A4 (0.55) | CYP3A4FAPCYP2D6 | |
| SCHEMBL20324454 | 0.85 | CYP3A4 (0.56) | CYP3A4FAPCYP2D6 | |
| SCHEMBL16020768 | 0.85 | CYP3A4 (0.67) | CYP3A4FAPCYP2D6 | |
| SCHEMBL16062941 | 0.85 | CYP3A4 (0.67) | CYP3A4FAPCYP2D6 | |
| SCHEMBL19470299 | 0.84 | CYP3A4 (0.71) | CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170304330-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-10-26 | — | — | US | disclosed |
| US-8835630-B1 | Acyclic nucleoside phosphonate diesters | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, A CALIFORNIA CORPORATION (US) | 2014-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170304330-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | NTPCR, PNP, TYMP | CYP3A4 3422/4885FAP 787/4885CYP2D6 3086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.