SCHEMBL16064008

SCHEMBL16064008

C=CCCCCCCC(=C)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.62
ABCC4 O15439 1/20 0.62
ALDH1A1 P00352 4/20 0.48
LMNA P02545 3/20 0.48
TSHR P16473 2/20 0.46
LPAR3 Q9UBY5 2/20 0.39
LPAR2 Q9HBW0 1/20 0.39
TRPA1 O75762 2/20 0.37
USP2 O75604 3/20 0.34
CYP3A4 P08684 2/20 0.34
RECQL P46063 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HPGD P15428 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
GMNN O75496 1/20 0.31
CYP1A2 P05177 1/20 0.31
POLB P06746 1/20 0.31
CYP2C9 P11712 1/20 0.31
ALOX15 P16050 1/20 0.31
APEX1 P27695 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17987904 1.00 MAPT (0.62) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL7460311 0.97
SCHEMBL393724 0.81 MAPT (0.58) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL8585201 0.81 MAPT (0.58) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL9007405 0.81 MAPT (0.58) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL9007415 0.81 MAPT (0.58) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL18585414 0.81 MAPT (0.58) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL8609151 0.81 MAPT (0.58) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL17178094 0.80 TSHR (0.41) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL6151574 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014145507-A1 A PROCESS FOR MAKING A 4-AMINO-4-OXOBUTANOYL PEPTIDE CYCLIC ANALOGUE, AN INHIBITOR OF VIRAL REPLICATION, AND INTERMEDIATES THEREOF ACHILLION PHARMACEUTICALS, INC. (US) 2014-09-18 WO disclosed