Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 20/20 | 0.89 |
| ▸ | CTSK | P43235 | 18/20 | 0.89 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22642984 | 0.95 | CTSC (0.87) | CTSCCTSK | |
| SCHEMBL16064496 | 0.94 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL16064507 | 0.93 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL16064774 | 0.92 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL16078827 | 0.92 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL16075225 | 0.92 | CTSC (0.88) | CTSCCTSK | |
| SCHEMBL22643398 | 0.91 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL16064726 | 0.91 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL16587707 | 0.91 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL16064773 | 0.91 | CTSC (1.00) | CTSCCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014140075-A1 | SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-09-18 | — | — | WO | disclosed |