Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 20/20 | 0.60 |
| ▸ | CTSK | P43235 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21013533 | 0.85 | CTSC (0.63) | CTSCCTSK | |
| SCHEMBL16064927 | 0.85 | CTSC (0.63) | CTSCCTSK | |
| SCHEMBL21013919 | 0.85 | CTSC (0.63) | CTSCCTSK | |
| SCHEMBL16092830 | 0.85 | CTSC (0.63) | CTSCCTSK | |
| SCHEMBL16064936 | 0.84 | CTSC (0.64) | CTSCCTSK | |
| SCHEMBL16064923 | 0.82 | CTSC (0.66) | CTSCCTSK | |
| SCHEMBL16064952 | 0.81 | CTSC (0.65) | CTSCCTSK | |
| SCHEMBL16092831 | 0.81 | CTSC (0.66) | CTSCCTSK | |
| SCHEMBL15083917 | 0.80 | CTSC (0.60) | CTSCCTSK | |
| SCHEMBL16071356 | 0.78 | CTSC (0.64) | CTSCCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014140081-A1 | SUBSTITUTED BICYCLIC 1-CARBOXYLIC-ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-09-18 | — | — | WO | disclosed |