Sugi Predict

Sugi Predict / Compounds / SCHEMBL16066429

SCHEMBL16066429

SCHEMBL16066429

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4ccc(-n5c6ccccc6c6cc7c(cc65)c5ccccc5n5c6ccccc6cc75)cc4)c3)n2)cc1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.36
▸ ATM Q13315 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ HDAC4 P56524 1/20 0.33
▸ GP6 Q9HCN6 1/20 0.31
▸ KMT2A Q03164 1/20 0.30
▸ RXRA P19793 1/20 0.30
▸ HAO1 Q9UJM8 1/20 0.30
▸ PTGER4 P35408 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16067226 1.00 KDM4E (0.36) KDM4EATML3MBTL1HDAC4GP6
SCHEMBL16066247 0.96 ATM (0.38) KDM4EATML3MBTL1HDAC4GP6
SCHEMBL16067231 0.96 ATM (0.40) KDM4EATML3MBTL1HDAC4KMT2A
SCHEMBL16066448 0.96 ATM (0.40) KDM4EATML3MBTL1HDAC4KMT2A
SCHEMBL16067020 0.94 KDM4E (0.37) KDM4EATML3MBTL1HDAC4GP6
SCHEMBL16066445 0.94 ATM (0.41) KDM4EATML3MBTL1HDAC4KMT2A
SCHEMBL16067218 0.94 ATM (0.41) KDM4EATML3MBTL1HDAC4KMT2A
SCHEMBL16067230 0.92 KDM4E (0.37) KDM4EATML3MBTL1KMT2APTGER4
SCHEMBL16066406 0.92 KDM4E (0.37) KDM4EATML3MBTL1KMT2A
SCHEMBL16067245 0.92 KDM4E (0.37) KDM4EATML3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014142488-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT INCLUDING SAME 주식회사 두산 (KR) 2014-09-18 — — WO disclosed