SCHEMBL16066992

SCHEMBL16066992

c1ccc(-c2ccc(-c3nc(-c4ccc(-c5ccccc5)cc4)nc(-n4c5ccccc5c5cc6c(cc54)c4ccccc4c4nc5ccccc5n64)n3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.47
ALDH1A1 P00352 7/20 0.47
HPGD P15428 7/20 0.47
MAPT P10636 4/20 0.45
POLB P06746 3/20 0.45
HSD17B10 Q99714 3/20 0.45
LMNA P02545 3/20 0.45
TP53 P04637 1/20 0.45
KMT2A Q03164 5/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MEN1 O00255 4/20 0.40
ATM Q13315 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
NCOA3 Q9Y6Q9 1/20 0.36
ADORA2A P29274 1/20 0.35
GAA P10253 1/20 0.34
HIF1A Q16665 1/20 0.34
TYMS P04818 1/20 0.34
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16066671 0.98 KDM4E (0.49) KDM4EALDH1A1HPGDMAPTPOLB
SCHEMBL16067106 0.97 KDM4E (0.46) KDM4EALDH1A1HPGDMAPTPOLB
SCHEMBL16066546 0.94 KDM4E (0.48) KDM4EALDH1A1HPGDMAPTPOLB
SCHEMBL16066697 0.93 KDM4E (0.45) KDM4EALDH1A1HPGDMAPTPOLB
SCHEMBL16066677 0.92 KDM4E (0.46) KDM4EALDH1A1HPGDMAPTPOLB
SCHEMBL16066663 0.91 KDM4E (0.47) KDM4EALDH1A1HPGDMAPTPOLB
SCHEMBL16066490 0.90 KDM4E (0.44) KDM4EALDH1A1HPGDMAPTPOLB
SCHEMBL16066964 0.90 KDM4E (0.46) KDM4EALDH1A1HPGDMAPTPOLB
SCHEMBL16066118 0.89 KDM4E (0.48) KDM4EALDH1A1HPGDMAPTPOLB
SCHEMBL16067083 0.89 KDM4E (0.48) KDM4EALDH1A1HPGDMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014142488-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT INCLUDING SAME 주식회사 두산 (KR) 2014-09-18 WO disclosed