Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 0.60 |
| ▸ | GSK3A | P49840 | 6/20 | 0.60 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.60 |
| ▸ | SRC | P12931 | 13/20 | 0.56 |
| ▸ | SYK | P43405 | 11/20 | 0.56 |
| ▸ | HCK | P08631 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19102004 | 0.93 | MAPK14 (0.61) | MAPK14GSK3AMAPK12SRCSYK | |
| SCHEMBL19225939 | 0.90 | GSK3A (0.76) | MAPK14GSK3AMAPK12SRCSYK | |
| SCHEMBL19226086 | 0.88 | MAPK14 (0.77) | MAPK14GSK3AMAPK12SRCSYK | |
| SCHEMBL19226068 | 0.88 | MAPK14 (0.77) | MAPK14GSK3AMAPK12SRCSYK | |
| SCHEMBL19750026 | 0.87 | MAPK14 (0.65) | MAPK14GSK3AMAPK12SRCSYK | |
| SCHEMBL19226193 | 0.86 | MAPK14 (0.70) | MAPK14GSK3AMAPK12SRCSYK | |
| SCHEMBL21131320 | 0.86 | MAPK14 (0.78) | MAPK14GSK3AMAPK12SRCSYK | |
| SCHEMBL19102036 | 0.86 | MAPK14 (0.69) | MAPK14GSK3AMAPK12SRCSYK | |
| SCHEMBL19101997 | 0.86 | MAPK14 (0.69) | MAPK14GSK3AMAPK12SRCSYK | |
| SCHEMBL15485245 | 0.85 | MAPK14 (0.80) | MAPK14GSK3AMAPK12SRCSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701670-B2 | Pyrazolyl-ureas as kinase inhibitors | RESPIVERT LIMITED (GB) | 2017-07-11 | — | — | US | disclosed |
| WO-2014140582-A1 | KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2014-09-18 | — | — | WO | disclosed |