Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LOX | P28300 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5198614 | 0.77 | TSHR (0.49) | MAPTKMT2AALDH1A1HTTMEN1 | |
| SCHEMBL4638550 | 0.77 | MAPT (0.47) | MAPTKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2606680 | 0.75 | KMT2A (0.52) | MAPTKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11125648 | 0.74 | MAPT (0.45) | MAPTALDH1A1LMNASMN1; SMN2LOX | |
| SCHEMBL11126605 | 0.74 | MAPT (0.45) | MAPTKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10402003 | 0.73 | KMT2A (0.50) | MAPTKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL31560169 | 0.73 | KMT2A (0.50) | MAPTKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2120202 | 0.73 | KMT2A (0.50) | MAPTKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16732 | 0.73 | KMT2A (0.50) | MAPTKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5421377 | 0.73 | KMT2A (0.50) | MAPTKMT2AALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014142273-A1 | DIHYDROPYRIDAZINE-3,5-DIONE DERIVATIVE | 中外製薬株式会社 (JP) | 2014-09-18 | — | — | WO | disclosed |