Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 20/20 | 0.58 |
| ▸ | HTR2C | P28335 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL355258 | 1.00 | MCHR1 (0.58) | MCHR1HTR2CKCNH2 | |
| SCHEMBL355849 | 0.93 | MCHR1 (0.60) | MCHR1HTR2CKCNH2 | |
| SCHEMBL355850 | 0.93 | MCHR1 (0.60) | MCHR1HTR2CKCNH2 | |
| SCHEMBL355016 | 0.86 | MCHR1 (0.61) | MCHR1HTR2CKCNH2 | |
| SCHEMBL355017 | 0.86 | MCHR1 (0.61) | MCHR1HTR2CKCNH2 | |
| SCHEMBL419783 | 0.86 | MCHR1 (0.68) | MCHR1HTR2CKCNH2 | |
| SCHEMBL419782 | 0.86 | MCHR1 (0.68) | MCHR1HTR2CKCNH2 | |
| SCHEMBL10082972 | 0.81 | MCHR1 (0.79) | MCHR1HTR2CKCNH2 | |
| SCHEMBL354971 | 0.81 | MCHR1 (0.60) | MCHR1HTR2CKCNH2 | |
| SCHEMBL354970 | 0.81 | MCHR1 (0.60) | MCHR1HTR2CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841290-B2 | Substituted tetrahydronaphthalenes, method for the production thereof, and use thereof as drugs | SANOFI (FR) | 2014-09-23 | — | — | US | disclosed |