Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 14/20 | 0.57 |
| ▸ | SCN5A | Q14524 | 13/20 | 0.57 |
| ▸ | SCN8A | Q9UQD0 | 12/20 | 0.57 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.48 |
| ▸ | SCN2B | O60939 | 3/20 | 0.48 |
| ▸ | SCN1B | Q07699 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30201091 | 0.84 | SCN1A (0.54) | SCN1ASCN5ASCN8ASCN9ASCN2B | |
| SCHEMBL29482006 | 0.81 | SCN1A (0.50) | SCN1ASCN5ASCN8ASCN9ASCN2B | |
| SCHEMBL17454965 | 0.78 | SCN1A (0.50) | SCN1ASCN5ASCN8ASCN9ASCN2B | |
| SCHEMBL30201470 | 0.75 | SCN1A (0.49) | SCN1ASCN5ASCN8ASCN9ASCN2B | |
| SCHEMBL17454914 | 0.75 | SCN1A (0.58) | SCN1ASCN5ASCN8ASCN9ASCN2B | |
| SCHEMBL29835236 | 0.74 | SCN1A (0.59) | SCN1ASCN5ASCN8ASCN9A | |
| SCHEMBL29481996 | 0.74 | SCN1A (0.54) | SCN1ASCN5ASCN8ASCN9A | |
| SCHEMBL1094422 | 0.74 | SCN1A (0.54) | SCN1ASCN5ASCN8ASCN9A | |
| SCHEMBL20237893 | 0.73 | SCN1A (1.00) | SCN1ASCN5ASCN8ASCN9ASCN1B | |
| SCHEMBL20259242 | 0.73 | SCN1A (0.78) | SCN1ASCN5ASCN8ASCN9ASCN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2974730-A1 | DRUG FOR RESPIRATORY DISEASES | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014142221-A1 | DRUG FOR RESPIRATORY DISEASES | 第一三共株式会社 (JP) | 2014-09-18 | — | — | WO | disclosed |