Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.67 |
| ▸ | FGFR4 | P22455 | 18/20 | 0.61 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.61 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16071541 | 0.91 | FGFR4 (0.67) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL16137314 | 0.89 | FGFR1 (0.63) | FGFR1FGFR4FGFR2FGFR3EGFR | |
| SCHEMBL16137331 | 0.88 | FGFR1 (0.62) | FGFR1FGFR4FGFR2FGFR3EGFR | |
| SCHEMBL17987685 | 0.88 | FGFR1 (0.62) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL16071492 | 0.87 | FGFR1 (0.82) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL16134009 | 0.84 | FGFR1 (0.69) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL16134008 | 0.83 | FGFR1 (0.67) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL16134013 | 0.82 | FGFR1 (0.65) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL16134015 | 0.82 | FGFR1 (0.69) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL19363621 | 0.81 | FGFR1 (0.54) | FGFR1FGFR4FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014144737-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | CELGENE AVILOMICS RESEARCH, INC. (US) | 2014-09-18 | — | — | WO | disclosed |