Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.54 |
| ▸ | FOLR1 | P15328 | 6/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 4/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13173078 | 0.97 | FOLH1 (0.56) | FOLH1FOLR1PTPN1HTR1ACHRM2 | |
| SCHEMBL13883450 | 0.97 | FOLH1 (0.56) | FOLH1FOLR1PTPN1HTR1ACHRM2 | |
| SCHEMBL29354043 | 0.97 | FOLH1 (0.57) | FOLH1FOLR1PTPN1HTR1ACHRM2 | |
| SCHEMBL17546355 | 0.96 | FOLR1 (0.52) | FOLH1FOLR1PTPN1HTR1ACHRM2 | |
| SCHEMBL14703624 | 0.95 | FOLH1 (0.52) | FOLH1FOLR1PTPN1HTR1ACHRM2 | |
| SCHEMBL12580185 | 0.95 | FOLR1 (0.53) | FOLH1FOLR1PTPN1HTR1ACHRM2 | |
| SCHEMBL13380231 | 0.95 | FOLH1 (0.53) | FOLH1FOLR1PTPN1HTR1ACHRM2 | |
| SCHEMBL16075076 | 0.93 | FOLR1 (0.50) | FOLH1FOLR1PTPN1HTR1ACHRM2 | |
| SCHEMBL11887211 | 0.93 | FOLH1 (0.52) | FOLH1FOLR1PTPN1HTR1ACHRM2 | |
| SCHEMBL13671525 | 0.93 | FOLH1 (0.52) | FOLH1FOLR1PTPN1HTR1ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9782497-B2 | Synthesis and composition of amino acid linking groups conjugated to compounds used for the targeted imaging of tumors | PURDUE RESEARCH FOUNDATION (US) | 2017-10-10 | — | — | US | disclosed |
| US-20170281800-A9 | SYNTHESIS AND COMPOSITION OF AMINO ACID LINKING GROUPS CONJUGATED TO COMPOUNDS USED FOR THE TARGETED IMAGING OF TUMORS | PURDUE RESEARCH FOUNDATION | 2017-10-05 | — | — | US | disclosed |
| US-20160339122-A1 | SYNTHESIS AND COMPOSITION OF AMINO ACID LINKING GROUPS CONJUGATED TO COMPOUNDS USED FOR THE TARGETED IMAGING OF TUMORS | PURDUE RESEARCH FOUNDATION (US) | 2016-11-24 | — | — | US | disclosed |
| US-9341629-B2 | Synthesis and composition of amino acid linking groups conjugated to compounds used for the targeted imaging of tumors | PURDUE RESEARCH FOUNDATION (US) | 2016-05-17 | — | — | US | disclosed |
| US-9333270-B2 | Synthesis and composition of amino acid linking groups conjugated to compounds used for the targeted imaging of tumors | PURDUE RESEARCH FOUNDATION (US) | 2016-05-10 | — | — | US | disclosed |
| US-20160011199-A1 | SYNTHESIS AND COMPOSITION OF AMINO ACID LINKING GROUPS CONJUGATED TO COMPOUNDS USED FOR THE TARGETED IMAGING OF TUMORS | PURDUE RESEARCH FOUNDATION | 2016-01-14 | — | — | US | disclosed |
| US-9061057-B2 | Synthesis and composition of amino acid linking groups conjugated to compounds used for the targeted imaging of tumors | PURDUE RESEARCH FOUNDATION (US) | 2015-06-23 | — | — | US | disclosed |
| US-20140271476-A1 | SYNTHESIS AND COMPOSITION OF AMINO ACID LINKING GROUPS CONJUGATED TO COMPOUNDS USED FOR THE TARGETED IMAGING OF TUMORS | PURDUE RESEARCH FOUNDATION (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140271482-A1 | SYNTHESIS AND COMPOSITION OF AMINO ACID LINKING GROUPS CONJUGATED TO COMPOUNDS USED FOR THE TARGETED IMAGING OF TUMORS | PURDUE RESEARCH FOUNDATION (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160011199-A1 | SYNTHESIS AND COMPOSITION OF AMINO ACID LINKING GROUPS CONJUGATED TO COMPOUNDS USED FOR THE TARGETED IMAGING OF TUMORS | EGFR, TIE1, ERBB2 | FOLH1 10/4885FOLR1 5/4885PTPN1 4453/4885 |
| US-20170281800-A9 | SYNTHESIS AND COMPOSITION OF AMINO ACID LINKING GROUPS CONJUGATED TO COMPOUNDS USED FOR THE TARGETED IMAGING OF TUMORS | EGFR, TIE1, ERBB2 | FOLH1 10/4885FOLR1 5/4885PTPN1 4453/4885 |
| US-20160339122-A1 | SYNTHESIS AND COMPOSITION OF AMINO ACID LINKING GROUPS CONJUGATED TO COMPOUNDS USED FOR THE TARGETED IMAGING OF TUMORS | EGFR, TIE1, ERBB2 | FOLH1 10/4885FOLR1 5/4885PTPN1 4453/4885 |
| US-20140271476-A1 | SYNTHESIS AND COMPOSITION OF AMINO ACID LINKING GROUPS CONJUGATED TO COMPOUNDS USED FOR THE TARGETED IMAGING OF TUMORS | EGFR, TIE1, ERBB2 | FOLH1 10/4885FOLR1 5/4885PTPN1 4453/4885 |
| US-20140271482-A1 | SYNTHESIS AND COMPOSITION OF AMINO ACID LINKING GROUPS CONJUGATED TO COMPOUNDS USED FOR THE TARGETED IMAGING OF TUMORS | EGFR, TIE1, ERBB2 | FOLH1 10/4885FOLR1 5/4885PTPN1 4453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.