Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | THRA | P10827 | 1/20 | 0.68 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | CA4 | P22748 | 1/20 | 0.65 |
| ▸ | CA6 | P23280 | 1/20 | 0.65 |
| ▸ | CA7 | P43166 | 1/20 | 0.65 |
| ▸ | TPMT | P51580 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29171434 | 1.00 | PLA2G4B (0.74) | PLA2G4BTSHRTHRATHRBSMPD1 | |
| SCHEMBL7273205 | 1.00 | PLA2G4B (0.74) | PLA2G4BTSHRTHRATHRBSMPD1 | |
| SCHEMBL29171441 | 1.00 | PLA2G4B (0.74) | PLA2G4BTSHRTHRATHRBSMPD1 | |
| SCHEMBL29171422 | 1.00 | PLA2G4B (0.74) | PLA2G4BTSHRTHRATHRBSMPD1 | |
| SCHEMBL2312195 | 1.00 | PLA2G4B (0.74) | PLA2G4BTSHRTHRATHRBSMPD1 | |
| SCHEMBL18682279 | 1.00 | PLA2G4B (0.74) | PLA2G4BTSHRTHRATHRBSMPD1 | |
| SCHEMBL9307551 | 1.00 | PLA2G4B (0.74) | PLA2G4BTSHRTHRATHRBSMPD1 | |
| SCHEMBL2329752 | 0.98 | TSHR (0.74) | PLA2G4BTSHRTHRATHRBSMPD1 | |
| Ethylene Glycol SCHEMBL11237315 | 0.96 | PLA2G4B (0.70) | PLA2G4BTSHRTHRATHRBSMPD1 | |
| SCHEMBL1750327 | 0.95 | TSHR (0.74) | PLA2G4BTSHRTHRATHRBSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117550979-B | Vanillic acid derivative and preparation method and application thereof | 广西师范大学 | 2025-03-11 | — | — | CN | disclosed |
| CN-117550979-A | Vanillic acid derivative and preparation method and application thereof | 广西师范大学 | 2024-02-13 | — | — | CN | disclosed |
| US-9873661-B2 | Small molecule malarial Aldolase-TRAP enhancers and glideosome inhibitors | NEW YORK UNIVERSITY (US) | 2018-01-23 | — | — | US | disclosed |
| US-9873661-B2 | Small molecule malarial Aldolase-TRAP enhancers and glideosome inhibitors | NEW YORK UNIVERSITY (US) | 2018-01-23 | — | — | US | disclosed |
| US-20140275088-A1 | SMALL MOLECULE MALARIAL ALDOLASE-TRAP ENHANCERS AND GLIDEOSOME INHIBITORS | THE JOHNS HOPKINS UNIVERSITY | 2014-09-18 | — | — | US | disclosed |
| US-20140275088-A1 | SMALL MOLECULE MALARIAL ALDOLASE-TRAP ENHANCERS AND GLIDEOSOME INHIBITORS | THE JOHNS HOPKINS UNIVERSITY | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275088-A1 | SMALL MOLECULE MALARIAL ALDOLASE-TRAP ENHANCERS AND GLIDEOSOME INHIBITORS | ALDOA, DERA, TALDO1 | PLA2G4B 3056/4885TSHR 4628/4885THRA 3605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.