SCHEMBL1607861

SCHEMBL1607861

C[Si]1(CCCNCCN)CCCCO1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.35
CA6 P23280 4/20 0.35
CA7 P43166 4/20 0.35
CA9 Q16790 4/20 0.35
CA14 Q9ULX7 4/20 0.35
CA5B Q9Y2D0 4/20 0.35
CA2 P00918 3/20 0.35
CA4 P22748 3/20 0.35
CA5A P35218 3/20 0.35
CA3 P07451 2/20 0.35
MEN1 O00255 2/20 0.33
RECQL P46063 2/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
ALOX15 P16050 2/20 0.32
CA1 P00915 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1568376 0.84
SCHEMBL1608257 0.82
SCHEMBL28246440 0.76
SCHEMBL7602540 0.73
SCHEMBL15513223 0.73 CA12 (0.42) CA12CA6CA7CA9CA14
SCHEMBL9128125 0.73
SCHEMBL27750803 0.73 CA12 (0.42) CA12CA6CA7CA9CA14
SCHEMBL29016685 0.72 TSHR (0.31)
SCHEMBL29233366 0.72 TSHR (0.31)
SCHEMBL10946089 0.72 TSHR (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4168128-A1 THICKENED ALKALYZATION COMPONENT FOR OXIDATIVE HAIR DYEING PRODUCT Henkel AG & Co. KGaA (DE) 2023-04-26 EP disclosed
EP-4168127-A1 THICKENED ALKALYZATION COMPONENT FOR OXIDATIVE HAIR LIGHTENING PRODUCT Henkel AG & Co. KGaA (DE) 2023-04-26 EP disclosed
CN-115867358-A Thickening and alkalizing component for oxidative hair lighteners 汉高股份有限及两合公司 2023-03-28 CN disclosed
CN-115697495-A Thickening and alkalizing component for oxidative hair dyes 汉高股份有限及两合公司 2023-02-03 CN disclosed
WO-2021254909-A1 THICKENED ALKALYZATION COMPONENT FOR OXIDATIVE HAIR DYEING PRODUCT HENKEL AG & CO. KGAA (DE) 2021-12-23 WO disclosed
WO-2021254803-A1 THICKENED ALKALYZATION COMPONENT FOR OXIDATIVE HAIR LIGHTENING PRODUCT HENKEL AG & CO. KGAA (DE) 2021-12-23 WO disclosed
EP-2651515-B1 AGENT FOR CHANGING THE COLOUR AND/OR FORM OF KERATINOUS FIBRES HENKEL AG & CO KGAA (DE) 2019-01-02 EP disclosed
EP-2559456-B1 Agent for treating and/or dying keratin fibres containing specific aminosilicones and alkalising agent HENKEL AG & CO KGAA (DE) 2018-09-05 EP disclosed
EP-2897576-B1 COMPOSITION FOR TREATING KERATINOUS FIBRES, COMPRISING SPECIFIC AMINOSILICONES, ACIDS AND DIRECT DYES HENKEL AG & CO KGAA (DE) 2017-03-01 EP disclosed
EP-2897576-A2 COMPOSITION FOR TREATING KERATINOUS FIBRES, COMPRISING SPECIFIC AMINOSILICONES, ACIDS AND DIRECT DYES Henkel AG & Co. KGaA (DE) 2015-07-29 EP disclosed
EP-1609821-A1 Amino-functional siloxane copolymer release agents for fuser members Xerox Corporation (US) 2005-12-28 EP disclosed
EP-1609822-A1 T-type amino functional release agent for fuser members Xerox Corporation (US) 2005-12-28 EP disclosed
CN-1092691-C Aqueous dispersions of organopolysiloxanes WACKER CHEMIE GMBH (DE) 2002-10-16 CN disclosed
CN-1183112-A Aqueous dispersions of organopolysiloxanes WACKER CHEMIE GMBH (DE) 1998-05-27 CN disclosed
US-5372854-A Maintaining uniform moisture content in cotton bales by spraying before compression with a dimethylsiloxane homo- or copolymer TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 1994-12-13 US disclosed
EP-0468626-B1 Cotton bales and method of producing same TAKEMOTO OIL & FAT CO LTD (JP) 1994-06-01 EP disclosed
US-5310616-A Toner compositions for electrostatic developers with organo siloxane resin DOW CORNING TORAY SILICONE CO., LTD. (JP) 1994-05-10 US disclosed
EP-0582281-A1 Toner compositions for electrostatic developers Dow Corning Toray Silicone Co., Ltd. (JP) 1994-02-09 EP disclosed
US-5188224-A Water insoluble, protective coating of polysiloxane adhesive coating attached to lint cotton TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 1993-02-23 US disclosed
US-4757121-A Two amine-substituted organopolysiloxanes, an epoxy-containing alkoxy silane, a monoepoxy compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed