Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15011725 | 0.97 | TSHR (0.53) | TSHRCA1CA2CA4LMNA | |
| SCHEMBL2254628 | 0.91 | TSHR (0.44) | TSHRCA1CA2CA4LMNA | |
| SCHEMBL28422261 | 0.85 | TSHR (0.53) | TSHRCA1CA2CA4LMNA | |
| SCHEMBL9283474 | 0.81 | TSHR (0.47) | TSHRCA1CA2CA4LMNA | |
| SCHEMBL13888941 | 0.81 | TSHR (0.64) | TSHRCA1CA2CA4LMNA | |
| SCHEMBL10795387 | 0.81 | TSHR (0.64) | TSHRCA1CA2CA4LMNA | |
| SCHEMBL15337087 | 0.81 | TSHR (0.64) | TSHRCA1CA2CA4LMNA | |
| SCHEMBL15484298 | 0.81 | TSHR (0.64) | TSHRCA1CA2CA4LMNA | |
| SCHEMBL13889159 | 0.81 | TSHR (0.64) | TSHRCA1CA2CA4LMNA | |
| SCHEMBL2154470 | 0.81 | TSHR (0.64) | TSHRCA1CA2CA4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140273264-A1 | EPOXY CHEMISTRY DERIVED MATERIALS AS MIXED MODE CHROMATOGRAPHY MEDIA, METHOD FOR THEIR SYNTHESIS AND USE | DIONEX CORPORATION | 2014-09-18 | — | — | US | disclosed |