⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16081686 | 1.00 | — | — | |
| SCHEMBL1564301 | 1.00 | — | — | |
| SCHEMBL21959485 | 1.00 | — | — | |
| SCHEMBL13241214 | 1.00 | — | — | |
| SCHEMBL15782446 | 1.00 | — | — | |
| SCHEMBL16379574 | 1.00 | — | — | |
| SCHEMBL14827845 | 1.00 | — | — | |
| SCHEMBL19301245 | 0.79 | — | — | |
| SCHEMBL19301347 | 0.79 | — | — | |
| SCHEMBL9650116 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170313745-A1 | INHIBITORS OF HEPATITIS C VIRUS | GILEAD SCIENCES, INC. | 2017-11-02 | — | — | US | disclosed |
| WO-2015191526-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2015-12-17 | — | — | WO | disclosed |
| WO-2014145095-A1 | MACROCYCLIC AND BICYCLIC INHIBITORS OF HEPATITIS C VIRUS | GILEAD SCIENCES, INC. (US) | 2014-09-18 | — | — | WO | disclosed |