Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 15/20 | 0.62 |
| ▸ | EGFR | P00533 | 5/20 | 0.60 |
| ▸ | LCK | P06239 | 2/20 | 0.56 |
| ▸ | LYN | P07948 | 1/20 | 0.56 |
| ▸ | KIT | P10721 | 1/20 | 0.55 |
| ▸ | FLT3 | P36888 | 1/20 | 0.55 |
| ▸ | ITK | Q08881 | 2/20 | 0.53 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.53 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16078937 | 0.89 | BTK (0.73) | BTKEGFRLCKLYNKIT | |
| SCHEMBL16075647 | 0.89 | BTK (0.73) | BTKEGFRLCKLYNKIT | |
| SCHEMBL16082981 | 0.81 | BTK (0.69) | BTKEGFRLCKLYNKIT | |
| SCHEMBL23226083 | 0.81 | BTK (0.74) | BTKEGFRLCKLYNKIT | |
| SCHEMBL23226086 | 0.81 | BTK (0.74) | BTKEGFRLCKLYNKIT | |
| SCHEMBL13063876 | 0.80 | LCK (0.69) | BTKEGFRLCKLYN | |
| SCHEMBL30353041 | 0.79 | BTK (0.71) | BTKEGFRLCKLYNKIT | |
| SCHEMBL12713510 | 0.79 | BTK (0.78) | BTKEGFRLCKLYNKIT | |
| SCHEMBL6430702 | 0.78 | BTK (0.76) | BTKEGFRLCKLYNITK | |
| SCHEMBL28685158 | 0.78 | BTK (0.75) | BTKEGFRLCKLYNKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014139970-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING A MEDICAMENT | JANSSEN PHARMACEUTICA NV (BE) | 2014-09-18 | — | — | WO | disclosed |