SCHEMBL16083

SCHEMBL16083

[CH]1CSCCS1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL447117 0.80
SCHEMBL1780820 0.74
SCHEMBL5046266 0.65
SCHEMBL452580 0.61
SCHEMBL27530 0.60
SCHEMBL20607 0.55
SCHEMBL270617 0.55
Hydrogen Sulfide SCHEMBL313917 0.55
SCHEMBL10809007 0.55
SCHEMBL4639 0.54

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8864 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023116734-A1 FUSED PYRROLIDINE COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF RESPIRATORY VIRAL INFECTIONS SHANGHAI MICURX PHARMACEUTICAL CO., LTD. (CN) 2023-06-29 WO claimed
CN-112300130-B Tricyclic compounds as BCR-ABL inhibitors 苏州亚盛药业有限公司 2023-04-25 CN claimed
US-20220227738-A1 KRAS G12C INHIBITORS AND USES THEREOF CALIFORNIA INSTITUTE OF TECHNOLOGY 2022-07-21 US claimed
EP-3287458-B1 HYBRID CYCLIC LIBRARIES AND SCREENING THEREOF UNIV JOHNS HOPKINS (US) 2022-07-13 EP claimed
CN-114728932-A Polyarylates as EGFR kinase inhibitors 江苏先声药业有限公司 2022-07-08 CN claimed
CN-114341127-A Aminopyrazine compounds as HPK1 inhibitors and uses thereof 百济神州有限公司 2022-04-12 CN claimed
EP-3972978-A1 KRAS G12C INHIBITORS AND USES THEREOF CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2022-03-30 EP claimed
CN-114096544-A KRAS G12C inhibitors and uses thereof 加州理工学院 2022-02-25 CN claimed
WO-2021104441-A1 POLYAROMATIC COMPOUND AS EGFR KINASE INHIBITOR 江苏先声药业有限公司 2021-06-03 WO claimed
US-10954273-B2 Hybrid cyclic libraries and screens thereof THE JOHNS HOPKINS UNIVERSITY (US) 2021-03-23 US claimed
US-5234946-A Anticholesterol, antilipemic BANYU PHARMACEUTICAL CO., LTD. (JP) 1993-08-10 US claimed
EP-0448078-A2 Substituted amine derivatives having anti-hyperlipemia activity BANYU PHARMACEUTICAL CO., LTD. (JP) 1991-09-25 EP claimed
EP-0395768-A1 SUBSTITUTED ALLYLAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE BANYU PHARMACEUTICAL CO., LTD. (JP) 1990-11-07 EP claimed
US-H563-H Use of sulfur-containing compounds for controlling plant parasitic nematodes RHONE POULENC NEDERLANDS B.V. (NL) 1989-01-03 US claimed
CN-86102621-A ACTINIC DITHIOFURAN RADICAL PESTICIDE 1987-01-21 CN claimed
US-4551472-A Unsymmetrical bis-carbamate compounds UNION CARBIDE CORPORATION (US) 1985-11-05 US claimed
EP-0035046-B1 NOVEL TETRAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND ANTI-ULCER COMPOSITION CONTAINING THE SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1985-10-02 EP claimed
EP-0079467-A1 N-substituted O-pyrazol-4-yl-carbamic-acid esters, process for their preparation and their use as biocides BAYER AG (DE) 1983-05-25 EP claimed
US-4264625-A INSECTICIDES, MITICIDES, NEMATOCIDES UNION CARBIDE CORPORATION (US) 1981-04-28 US claimed
US-4169894-A INSECTICIDES, MITICIDES, NEMATOCIDES UNION CARBIDE CORPORATION (US) 1979-10-02 US claimed