Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 20/20 | 0.69 |
| ▸ | AKT2 | P31751 | 13/20 | 0.69 |
| ▸ | AKT3 | Q9Y243 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27232039 | 0.91 | AKT1 (0.68) | AKT1AKT2AKT3 | |
| SCHEMBL2192796 | 0.82 | AKT1 (1.00) | AKT1AKT2AKT3 | |
| SCHEMBL16087427 | 0.81 | AKT1 (0.63) | AKT1AKT2AKT3 | |
| Hydrochloric Acid SCHEMBL2173899 | 0.81 | AKT1 (1.00) | AKT1AKT2AKT3 | |
| SCHEMBL2178315 | 0.80 | AKT1 (0.66) | AKT1AKT2AKT3 | |
| SCHEMBL2176351 | 0.80 | AKT1 (0.78) | AKT1AKT2AKT3 | |
| SCHEMBL2193736 | 0.80 | AKT1 (0.83) | AKT1AKT2AKT3 | |
| SCHEMBL2173820 | 0.80 | AKT1 (0.80) | AKT1AKT2AKT3 | |
| SCHEMBL16087364 | 0.80 | AKT1 (0.71) | AKT1AKT2AKT3 | |
| SCHEMBL2194106 | 0.79 | AKT1 (0.81) | AKT1AKT2AKT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519522-B1 | SUBSTITUTED IMIDAZOPYRIDINYL-AMINOPYRIDINE COMPOUNDS | ARQULE INC (US) | 2014-09-24 | — | — | EP | disclosed |