Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 12/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16087652 | 1.00 | PTH1R (0.86) | PTH1R | |
| SCHEMBL849104 | 1.00 | PTH1R (0.86) | PTH1R | |
| SCHEMBL849103 | 1.00 | PTH1R (0.86) | PTH1R | |
| SCHEMBL847518 | 0.94 | PTH1R (0.91) | PTH1R | |
| SCHEMBL849538 | 0.94 | PTH1R (0.85) | PTH1R | |
| SCHEMBL849539 | 0.94 | PTH1R (0.85) | PTH1R | |
| SCHEMBL850997 | 0.93 | PTH1R (0.84) | PTH1R | |
| SCHEMBL850253 | 0.93 | PTH1R (0.84) | PTH1R | |
| SCHEMBL850127 | 0.93 | PTH1R (1.00) | PTH1R | |
| SCHEMBL851204 | 0.91 | PTH1R (0.84) | PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433940-B9 | SPIROIMIDAZOLONE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2015-10-28 | — | — | EP | claimed |
| EP-2433940-B1 | SPIROIMIDAZOLONE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2014-09-24 | — | — | EP | claimed |