⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871658 | 0.84 | — | — | |
| SCHEMBL17519800 | 0.65 | — | — | |
| SCHEMBL20437598 | 0.60 | TSHR (0.31) | — | |
| SCHEMBL4954929 | 0.60 | — | — | |
| SCHEMBL14127396 | 0.60 | TSHR (0.31) | — | |
| SCHEMBL13213372 | 0.59 | GBA1 (0.50) | — | |
| SCHEMBL12289585 | 0.59 | GBA1 (0.50) | — | |
| SCHEMBL8994285 | 0.59 | GBA1 (0.50) | — | |
| SCHEMBL14409033 | 0.57 | GBA1 (0.56) | — | |
| SCHEMBL12347589 | 0.57 | GBA1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044641-A2 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |
| WO-2014144169-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-18 | — | — | WO | disclosed |